🇺🇸 United States Episodes

Jimmy Lin is developing technologies to catch cancer months to years before current methods. He shares a breakthrough technique that looks for small signals of cancer's presence via a simple blood test, detecting the recurrence of some forms of the disease 100 days earlier than traditional methods. It could be a ray of hope in a fight where early detection makes all the difference.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

My guest this week is a version of me—a funnier, cooler version who has a PhD and served as an active duty marine. Lots of you will already be familiar with Wes Gray, and those of you who are not are in for a treat. Wes is the founder of Alpha Architect, a firm which manages quantitative equity strategies for clients using factors like value and momentum. He also advocates for a more concentrated, pure approach to factor investing, which listeners know is music to my ears. While we share a lot of the same views on markets and investing, you will still find this refreshing. The conversation was easy to structure--I just took all the questions clients and prospective investors always ask of me and my firm, and turned them on Wes. These range from very specific questions on quant investing to big existential ones. I listened to this on a long drive home and laughed out loud in the car at least 5 times. You are going to love it all. I close this introduction by offering you an opportunity which is not for the faint of heart. On September 16th, I will be joining Wes and his crew on a 28-mile trek called “March for the Fallen” which is a small but important way of honoring those who have given their lives in service of our country. Wes and I invite you to join as well. If you are interested, check out the post on Wes’s site with all the details. I will link to it in the shownotes at investorfieldguide.com/wes. If you are still interested, then email me with the subject heading “March for the Fallen.” I told you Wes is a much cooler version of me, and true to form he will be doing the hike with a 40-pound rucksack. I will be doing the version without a rucksack. Either way, it will be a day of comradery and remembrance that we won’t soon forget. Join us.   Books Referenced The Devil Dogs at Belleau Wood: U.S. Marines in World War I Thinking, Fast and Slow   Online References The Limits of Arbitrage   Show Notes 3:07 – (First question) – Exploring the mindset that is ingrained into Marines 3:16 – The Devil Dogs at Belleau Wood: U.S. Marines in World War I 5:27 – Most memorable experience growing up in the mountains of Colorado 6:29 – What experiences in the military have transferred to what Wes sees in the public markets 6:48 – Thinking, Fast and Slow 7:51 – Wes’s first foray into stocks 10:51 – What was the transition into the quantitative investing space 12:29 – How Wes would describe quantitative investing and what the landscape looks like today 17:10 – What is the nature of the strategies Wes uses, like high-frequency and market-making, and what makes them stand out in those 20:57 – What about the human capital arms race in this space and how different firms are attracting the top talent 23:21 – What the approach is for Wes and what his research suggests is the best predictor of performance in stocks 25:36 – Wes’s approach to portfolio construction 33:19 – What is the thinking behind the number of and the size of names in the QVAL ETF 36:20 – Why the data suggests momentum is the better pick 37:36 – Why price-to-book sucks relative to other value factors 39:55 – What things worry Wes about the future of this strategy 44:39 – How does Wes think about research and what to explore next. 50:05 – Who would Wes have manage his money since he thinks Vanguard is not the best choice 57:01 – Exploring his firm Alpha Architect, how it started and has evolved since launch 57:39 – The Limits of Arbitrage 1:08:15 – How the influx of people to passive investments are impacting the overall market, especially for active investment strategies 1:13:13 – Wes’s most memorable day of his career both in the military and as an investor 1:17:19– Kindest thing anyone has ever done for Wes     Learn More For more episodes go to InvestorFieldGuide.com/podcast.  Sign up for the book club, where you’ll get a full investor curriculum and then 3-4 suggestions every month at InvestorFieldGuide.com/bookclub Follow Patrick on twitter at @patrick_oshag

Nick Swardson is an actor, stand-up comedian, screenwriter and producer. The second season of his Comedy Central series "Typical Rick" is available now on YouTube -- https://www.youtube.com/playlist?list=PLD7nPL1U-R5qiy2BvfPO1eXrGgwbs5oSp Learn more about your ad choices. Visit podcastchoices.com/adchoices

There are the things that you carefully plan when it comes to an IPO -- the who (the bankers, the desired institutional investors); the what (the pricing, the allocations); and the when (are we ready? is this a good public business?). But then there ...

Loneliness doesn't always stem from being alone. For architect Grace Kim, loneliness is a function of how socially connected we feel to the people around us -- and it's often the result of the homes we live in. She shares an age-old antidote to isolation: cohousing, a way of living where people choose to share space with their neighbors, get to know them, and look after them. Rethink your home and how you live in it with this eye-opening talk.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Born with a genetic visual impairment that has no correction or cure, Susan Robinson is legally blind (or partially sighted, as she prefers it) and entitled to a label she hates: "disabled." In this funny and personal talk, she digs at our hidden biases by explaining five ways she flips expectations of disability upside down.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Erik Brynjolfsson, MIT Sloan School professor, explains how rapid advances in machine learning are presenting new opportunities for businesses. He breaks down how the technology works and what it can and can’t do (yet). He also discusses the potential impact of AI on the economy, how workforces will interact with it in the future, and suggests managers start experimenting now. Brynjolfsson is the co-author, with Andrew McAfee, of the HBR Big Idea article, “The Business of Artificial Intelligence.” They’re also the co-authors of the new book, “Machine, Platform, Crowd: Harnessing Our Digital Future.

Why do so many companies make bad decisions, even with access to unprecedented amounts of data? With stories from Nokia to Netflix to the oracles of ancient Greece, Tricia Wang demystifies big data and identifies its pitfalls, suggesting that we focus instead on "thick data" -- precious, unquantifiable insights from actual people -- to make the right business decisions and thrive in the unknown.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

In the early days of your startup, it feels like everything's on fire all the time. Real talk: if you try to put out every fire, every day, you’ll only burn yourself out. The best entrepreneurs know how to let some fires burn. Selina Tobaccowala, veteran leader of Evite, SurveyMonkey and the fitness startup Gixo, shares her insights on how to choose which problems not to solve, and how to conserve your energy for the biggest blazes.Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Right now, billions of neurons in your brain are working together to generate a conscious experience -- and not just any conscious experience, your experience of the world around you and of yourself within it. How does this happen? According to neuroscientist Anil Seth, we're all hallucinating all the time; when we agree about our hallucinations, we call it "reality." Join Seth for a delightfully disorienting talk that may leave you questioning the very nature of your existence.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Here’s what we know: There’s a pair (father and son) of Russian scientists trying to resurrect (or rather, "rewild") an Ice Age (aka Pleistocene era) biome (grassland) complete with (gene edited, lab-grown) woolly mammoths (derived from elephants). I...

My guest this week is Rishi Ganti, who invests in what he calls esoteric assets. I'm not sure what to do other than laugh in amazement at his professional credentials -- PhD in economics, CFA, CPA, lawyer, speaks six languages, and so on. The best part is he isn't lording those over anyone and in fact casts some shade on the whole idea of credentials in our conversation. He just did it all because he's a learning fiend. Rishi's core idea about markets is this: avoid markets at all costs. As he explains off the bat, the minute there are multiple buyers for anything, prices get efficient very quickly and there opportunity to find alpha shrinks. Instead he searches for what esoteric assets: things without a market, orphaned assets that require high human capital and human touch. We explore several interesting examples, from charter school financing to A stark realization I had during he episode is how big the worlds asset base is. Almost all of our attention goes to the most highly refined ones: stocks and bonds. But there is a whole other world out there. The closing sections, on what Rishi would do if not investing, and his answer for the kindest thing anyone has done for him were among the best answers I've heard.   Show Notes 3:30 – (First question) – Rishi’s broad take on markets and whether or not he really likes them 5:30 – Defining esoteric markets 8:31 – Looking at the mountain of assets that are most impacted or made most efficient by markets and how Rishi describes each level of that pyramid 12:28 – Looking at an esoteric asset at the early part of Rishi’s career 16:23 – Why is there little competition in these types of investment opportunities 23:06 – How they created a market and turned an esoteric asset into a return opportunity, starting with the charter school funding example 31:54 – Looking at how this is done internationally 38:55 – What they consider a platform 41:08 – How they are able to provide their service and skirt the government, legally 44:18 – A simplified explanation of what Orthogon does 50:30 – What are the main reasons people don’t want to go down this road since it seems like an obvious choice 59:00 – Looking at the most memorable experiences in esoteric investing 1:01:10 – What value has Rishi found in his extensive education, credentials, and certifications 1:07:31 – Another topic that Rishi finds interesting and he’d want to lecture on if he could other than investing. 1:09:48 – What is the right formula and types of goals you should consider in planning your life 1:14:39 – Kindest thing anyone has done for Rishi Learn More For more episodes go to InvestorFieldGuide.com/podcast.  Sign up for the book club, where you’ll get a full investor curriculum and then 3-4 suggestions every month at InvestorFieldGuide.com/bookclub Follow Patrick on twitter at @patrick_oshag

Ari Shaffir & Joe do a podcast while hiking to celebrate the release of Ari's new two-part Netflix special "Double Negative" on July 18th. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Climate change is real, case closed. But there's still a lot we don't understand about it, and the more we know the better chance we have to slow it down. One still-unknown factor: How might clouds play a part? There's a small hope that they could buy us some time to fix things ... or they could make global warming worse. Climate scientist Kate Marvel takes us through the science of clouds and what it might take for the earth to break its own fever.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

In the age of virality, what does it actually mean to be popular? When does popularity -- or good product design, for that matter -- cross over from desire and engagement... to addiction? Journalist and editor Derek Thompson, author of Hit Makers: Th...

What are our screens and devices doing to us? Psychologist Adam Alter has spent the last five years studying how much time screens steal from us and how they're getting away with it. He shares why all those hours you spend staring at your smartphone, tablet or computer might be making you miserable -- and what you can do about it.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Phil Knight, former chair and CEO of Nike, tells the story of starting the sports apparel and equipment giant after taking an entrepreneurship class at Stanford and teaming up with his former track coach, Bill Bowerman. Together (and with the help of a waffle iron) they changed how running shoes are designed and made. Knight discusses the company's enduring culture of innovation, as well as the succession process that led to former runner and Nike insider Mark Parker becoming CEO.

Rivers are one of nature's most powerful forces -- they bulldoze mountains and carve up the earth, and their courses are constantly moving. Understanding how they form and how they'll change is important for those that call their banks and deltas home. In this visual-packed talk, geoscientist Liz Hajek shows us how rocks deposited by ancient rivers can be used as a time machine to study the earth's history, so we can figure out how to more sustainably live on it today.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Ben & David cover the creation of the gaming world’s equivalent of the 70’s rock supergroup: the 2008 merger of Blizzard and Activision. We tell the story from the Blizzard perspective, tracing the history of one of the most innovative companies in the business from humble beginnings at the hands of UCLA undergrads, to surviving multiple acquisition rollups (including at one point being owned by the French national water company), to joining ultimately with Activision to form the largest gaming company in the world, all while inventing multiple game genres that define the industry as we know it today. Sponsors:WorkOS: https://bit.ly/workos25Sentry: https://bit.ly/acquiredsentryServiceNow: https://bit.ly/acquiredsnMore Acquired!:Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCTopics covered include: Blizzard’s founding in 1991 as "Silicon & Synapse” by recent UCLA grads Allen Adham, Frank Pearce, and Mike MorhaimeThe team’s first projects making ports for other games, including Battle Chess on the Commodore 64Early success on the Super Nintendo with Rock & Roll Racing and The Lost VikingsOrigin of the Real-Time Strategy game genre (“RTS”) and Blizzard’s fist mega-hit, Warcraft Blizzard’s crazy corporate ownership changes over the yearsDevelopment of further legendary game franchises like Diablo and Starcraft, along with sequels to Warcraft and the rise of the rise of player moddingEmergence of the Multiplayer Online Battle Arena genre (“MOBA”) from the Warcraft III modding community, and its growth into one of the biggest sectors in the games and esports industries todayBlizzard’s role in developing the concept of online gaming, from early hacks to play against friends to World of Warcraft and Massively Multiplayer Online Role-Playing Games (“MMORPG’s”)The 2008 merger with storied gaming company Activision Growth and success since the merger, including the launch of new game franchises Hearthstone, Heroes of the Storm and Overwatch  The Carve Out: Ben:  Dick Costolo on Vanity Fair’s  Inside the Hive  podcastDavid: Nellie and Joe's 100% Natural Key Lime Juice (tip:  buy in bulk from Walmart/Jet)

Ben O'Brien is the hunting marketing manager at YETI Coolers, he was also the executive editor for Petersen's Hunting. Learn more about your ad choices. Visit podcastchoices.com/adchoices