The creation of each new biotechnology enables a tool, a therapy, or a diagnostic: a molecule, a protein, an app, a platform. And the process underneath isn't just complex in the science and engineering of it, but in the go to market. So who are the...

Hypothesis, test, revise -- that's science. Engineering, however, doesn't quite go that way: You have parts you know and understand (like legos), and then you use those parts to design and build something (like bridges). But the key is that when scie...

with Lisa Hawke (@ldhawke) and Steven Sinofsky (@stevesi) Given concern around data breaches, the EU Parliament finally passed GDPR (General Data Protection Regulation) after four years of preparation and debate; it goes into enforcement on May 25, ...

with Nicole Forsgren (@nicolefv), Jez Humble (@jezhumble) and Sonal Chokshi (@smc90) From the old claim that "IT doesn't matter" and question of whether tech truly drives organizational performance, we've been consumed with figuring out how to measu...

Few operators become VCs, and even fewer go back to leading companies... so how does these perspectives change how one leads? Obviously, it's a lot easier to think of a solution than execute on one... but then how does a leader empower one's team to ...

Leadership is not just about management, but about passion, a bit of humor, and resilience. General partner Peter Levine and Dick Costolo (entrepreneur, former CEO of Twitter, and erstwhile comedian) share their thoughts on the topic in this episode ...

Focusing only on the technical, "crunchy, wonky stuff" behind policies or products sometimes misses the humanity at the center of why we're doing the thing in the first place. Because systems -- whether algorithms and artificial intelligence, or capi...

with Kristen Fortney (@kpfortney), Jeff Kaditz (@jeffkaditz), David Sinclair (@davidasinclair), and Hanne Tidnam (@omnivorousread) Even without a mythical fountain of youth, scientific advances have already dramatically increased how long humans liv...

with Cristina Cordova (@cjc), Augusto Marietti (@sonicaghi), Laura Behrens Wu (@laurabehrenswu), and Sonal Chokshi (@smc90) APIs (application programming interfaces), observe the guests in this episode of the a16z Podcast, can be described as everyt...

What happens when monolithic architectures are broken down into containers and microservices (or when things are broken down into smaller units, not just in infrastructure but perhaps even in company structure too)? From building more dynamic website...

When most people think of space, they think of outer space: Mars, billionaires with rockets, and the “final frontier”. But space innovation is actually playing out right now -- in an immediate and more accessible way, thanks to techonologies getting ...

with Joel de la Garza, Stina Ehrensvärd, Niels Provos, and Martin Casado Given the heated discussions around security and the c-word (“cyber”), it’s hard to figure out what the actual state of the industry is. And clearly it’s not just an academic e...

with Martin Casado (@martin_casado), Michel Feaster (@michelfeaster) and Sonal Chokshi (@smc90) The purpose of category creation, argue the guests in this episode of the podcast, isn't just about making a dent in the way companies work and changing ...

with Adam Bry (@adampbry), Chris Dixon (@cdixon), and Hanne Tidnam (@omnivorousread) Now that we've finally reached the age of the truly autonomous commercial small drone -- and in this case, a self-flying camera -- what happens when you take the pi...

Once upon a time it was inconceivable that a company in Silicon Valley could make content that was any good; the running joke, shares Marc Andreessen, "was like, what are we gonna do -- we're gonna film a router instruction manual? It was just an abs...

Every large company -- especially ones that have been around for a long time -- goes through multiple cycles of change. But how do you know where to go next, and when, and how? The management literature is full of case studies, research, and of cours...

As people begin to gain access to information that was previously left to only trained specialists, a new set of asset classes are being created -- and they are changing the way we think about everything from banking to customizing portfolios and mor...

In 2017 The Economist declared data to be the world's most valuable resource. And yet “data insight” is one of those phrases that, while important, is now so ubiquitous it’s been numbed of meaning. So how do you actually get the most meaningful insig...

The battle between every startup and incumbent comes down to whether the startup gets distribution before the incumbent gets innovation, oft observes a16z general partner Alex Rampell. But how does this play out when most of the players, big and smal...

There was a lot of hype about VR ad then it seemed to go pretty quiet. So where are we right now? Bigscreen founder Darshan Shankar and a16z general partner Chris Dixon take the pulse on VR, AR, and mixed reality -- especially where it's going the ne...