There are those who would say that Aubrey de Grey is out to cure death, but what this former artificial intelligence specialist turned gerontologist is really focused on is health -- and the side effect of health is living a lot longer. In this segm...

The title of world's financial capital bounces back and forth between London and New York. This year London has bragging rights, but does being the word's center of gravity for finance mean so-called "fintech" companies will naturally flow from that ...

What is A.I. or artificial intelligence but the 'space of possible minds', argues Murray Shanahan, scientific advisor on the movie Ex Machina and Professor of Cognitive Robotics at Imperial College London. In this special episode of the a16z Podcast...

Blockchain without bitcoin? It's a debate as old as the cryptocurrency itself (which, to be honest, isn't that old). Given that bitcoin is not just a digital bearer instrument/token but is a network, a distributed ledger, a protocol, the question of ...

What began as a scientific approach to creating and managing startups has now become a worldwide movement for companies of all sizes -- and for creating (or rather rediscovering) entrepreneurs in all places. Not just inside startups, not just for sof...

There's a "game" being played right now among lawmakers and tech companies around policy issues, and as tech touches everything, everyone has to play some version of it. Even if the game keeps changing. Even if they don't want to. Or do they? What...

Telepresence. It's an ugly, outdated word for an attractive and current/ emerging phenomenon where people can work from anywhere, anytime. It's technology for the way we work today. But is it as easy as adding good tech to a constantly evolving prob...

"The most boring yet valuable podcast in a16z history" -- he (our guest Joe Grundfest) said it, not we! That’s because in this episode of the a16z Podcast, Stanford law professor and former SEC commissioner Grundfest -- and securities litigation law...

It's easy to argue for "choosing possibility" when it comes to addressing diversity and inclusion in tech when certain people have access to networks and others don't. BoardList -- more of a talent marketplace than a "list" per se -- is an effort to ...

Disruption is such an overused buzzword. But the word itself does have meaning: As defined by the Oxford and Merriam-Webster dictionaries, it is a "disturbance...that interrupts an event, activity, or process" and that causes something "to be unable ...

Technology is a progression of new ideas and new platforms gobbling up the one that came before. In the world of computers we went from mainframes to mini computers to PCs. And then came the mobile phone, which, in the form of the smartphone, has dwa...

This special episode of the a16z Podcast is based on a Q&A from an early screening we hosted of OWN (Oprah Winfrey Network)'s "Belief", which just premiered and airs over seven consecutive nights. This week-long documentary series depicts how people ...

We just witnessed the largest acquisition in tech history, and before Dell made it happen, it would have been hard to imagine. Not so much that the two companies would come together, but that the much smaller Dell would be buying its larger peer EMC....

The place where Apache Spark was born, UC Berkeley’s AMPLab has not just created a major open source software platform, it’s spun out more than its share of ground-breaking companies (full disclosure: a16z has invested in three of them). So how did ...

Getting denied another round of NSF funding in the early days of Mosaic turned out to be a huge catalyst to start a company around the fledgling web browser, says Marc Andreessen. That company was Netscape. Andreessen was still at the University of...

There is a stream of the world's largest companies coming to Silicon Valley looking for innovation. But how do they find it, and then, how do they bring it back home? a16z's Elizabeth Weil joins this segment of the pod to lay out what the Fortune 500...

Mention Patrick Byrne, the founder and CEO of Overstock.com, and you’ll elicit a strong opinion. In 2004, one hedge fund manager labeled Byrne the most hated man on Wall Street -- a label he wears proudly. Byrne started Overstock.com in 1999, and ...

Podcasts and podcasting have been around a while, but seem to be going through a renaissance of sorts -- partly enabled by connected cars and other technologies. But how do we discover podcasts; is the ideal atomic unit the show, or an individual epi...

Financial services are overdue for an overhaul. With a16z's newest general partner, Alex Rampell (who just officially started), this segment of the podcast explores the world of fintech... How software backed up by data is being brought to bear on le...

Apple included support for ad blocking in its recent iOS 9 update, and for many that prompted discussions around an age-old question: Is traditional advertising a viable business model for content -- and if it isn’t, what has a shot at replacing it? ...