Moderna's Covid-19 vaccine would not have scaled without Ginkgo Bioworks. Reshma Shetty, co-founder and COO of Ginkgo – slated to go public via SPAC acquisition at a reported $15 billion valuation – explains how biotech innovation can build a better future now. Ginkgo's platform already serves industries from food and agriculture, to materials, to healthcare. Shetty acknowledges that engineering genes is a high stakes pursuit, and says Ginkgo is trying to pair the ambition of Silicon Valley with a "higher level of care" than consumer tech companies like social media have demonstrated. The key, Shetty says, is creating an unstable equilibrium – propelling progress but not at the expense of principles.Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You can make your social impact and your bottom line work hand-in-hand. But you'll have to be as creative and innovative about your company's values as you are about the business itself. Howard Schultz, chair and former CEO of Starbucks, not only changed how America wakes up, but set new standards for employee benefits. From offering college tuition to American employees to providing health care for employees' parents in China, Howard has always been one step ahead of the social impact curve.Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As a new leader, how do you honor an established brand while trying to shepherd it into the next era? Las Vegas Raiders’ president Sandra Douglass Morgan took the helm amid a front office scandal and a team new to the desert. Morgan talks about prioritizing customers over all else, taking risks at the beginning of a new venture, and why to bet on yourself from the moment you apply for a job. Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Innovation is the lifeblood of the startup — from product to processes and culture to creativity. But innovation is just as essential for scale companies. So how do you keep the innovation flywheel spinning at all levels of scale? The answer according to Linda Yates is to seed every level of your company with an intrapreneurial mindset. As CEO of Mach49, an incubator for large global companies, Linda shares her vast experience and strategies for injecting intrapreneurial thinking and bias-to-action across hundreds of large-scale organizations.Read a transcript of this episode: https://mastersofscale.com/think-like-an-intrapreneur-linda-yates/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hybrid, remote, in-person, a little bit of everything? Work has transformed into a giant experiment. Priya Parker, expert facilitator and author of The Art of Gathering: How We Meet and Why It Matters, shares her advice on how to manage the new hybrid workplace. Where to start? Focus first, she suggests, on making your meetings better.Read a transcript of this interview: https://mastersofscale.com/mastering-the-hybrid-workplace-priya-parker/Get a free copy of Priya Parker's guide to hybrid gatherings: https://www.priyaparker.com/the-hybrid-gathering-guideSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Taking risks can be the catalyst for immense scale or dire straits. Avoiding taking any risks at all leads to stagnancy and empowered competitors. The key is to know which risks are worth taking, and when and how to take them. This episode highlights the best conversations we’ve had recently about taking advantage of risk and how fortune favors the brave. Featuring New Georgia Project’s Stacey Abrams, Care.com’s Sheila Lirio Marcelo, Bankable Productions & SMiZE Cream’s Tyra Banks, MetricStream’s Shellye Archambeau, Moderna’s Stéphane Bancel, Digital Undivided’s Kathryn Finney, Ellevest’s Sallie Krawcheck, and American Express’s Ken Chenault. Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

After slashing his NYC restaurant team from 2,400 people to just 45 in the teeth of the pandemic, Danny Meyer has rebuilt Union Square Hospitality Group back to its former size. But in his fifth appearance on Rapid Response since Covid struck, Danny says he isn’t yet triumphant. With inflation creating fresh challenges even at Shake Shack, Danny shares lessons on the good and bad of leading through a crisis, plus explains why he’s handed off his CEO title — and where he finds inspiration to fuel new innovations.Read a transcript of this interview: https://mastersofscale.com/how-covid-lessons-get-tested-by-inflation-danny-meyer/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For truly sustainable long-term growth, you must prioritize your mission over your product — even if that means letting your product go. Noom founder and CEO Saeju Jeong has repeatedly turned his back on successful products in the name of his mission to help as many people as possible live healthier lives. In this episode, Saeju brings to life many of these make-or-break moments, and how his dedication to mission has driven his scale journey.Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When markets are in turmoil, you can’t rely on business as usual, but that doesn’t mean you should panic. As the housing climate has turned volatile, rest estate marketplace Zillow has been forced to rethink some priorities, while doubling down on others. Zillow president Susan Daimler talks about the importance of a strategy focused on the future, despite layoffs and pullbacks, and how maintaining a clear shared mindset has enabled forward progress in a challenging climate. Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can a small entrepreneur make an impact within a massive, complex system, like healthcare or education? What's the best framework to amplify the positive side of having co-founders and avoid the negatives? Reid Hoffman and Bob Safian answer these and more questions from small business owners in the Masters of Scale community. Plus: in our Need to Know segment, Reid & Bob take on a burning question: How can Black founders beat the odds and find funding?Learn more about becoming a Masters of Scale Member: www.mastersofscale.com/membersRead a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Partnerships can be the secret weapon to rocketing your company to the next level. That’s what Cathy Zoi discovered when she became the CEO of charging station network, EVgo. Whether it be partnering with grocery and department stores, or aligning with the Tesla customer-base, targeting allies and collaborators are a crucial catalyst for how EVgo has grown to become the nation’s largest public EV charging network. Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

To achieve massive scale, you don’t just need founders, you also need a re-founder – someone to come in at a later stage to keep the mission and culture on track. As Microsoft’s third CEO ever — after Bill Gates and Steve Ballmer — Satya Nadella is doing just that. He’s fostered a culture at Microsoft that rewards new ideas and makes room for feedback. Satya discusses how, as Chairman and CEO, he has transformed Microsoft from a cutthroat culture towards embracing social networks, collaboration, and cloud. Plus, Satya and Reid reminisce about the early conversations that led to Microsoft’s acquisition of LinkedIn. With guest David Mandel, showrunner of Veep.Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Too many businesses and organizations spend time planning and not enough in action, especially in times of emergency. José Andrés, world-famous chef and founder of the nonprofit World Central Kitchen, proves the value of fast action through his work, including his recent time in Ukraine serving over 150 million meals. José thinks businesses should flatten their power structure and treat food as a national security issue, even in places like the U.S.  Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When is it time to double down on your instincts, and when is it time to open yourself up to feedback? Sometimes it comes down to a hard call… that you might get totally wrong. In Part Two of our episode with Patreon’s Jack Conte, you’ll hear how he was able to raise capital by telling his authentic story after a series of pitches that went disastrously wrong! And you’ll hear how his worst mistake as a founder helped him reconnect with Patreon’s mission and community, and build Patreon into a $4B company. How can being wrong accelerate your business? It takes running at the solution with insatiable curiosity. Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When it comes to racial justice, many companies and organizations haven't matched their reality to their words. Rashad Robinson, the president of Color of Change, the largest online racial justice organization in the U.S., is holding major corporations accountable. Hear Rashad talk through the difficulties of changing systems from Hollywood, Silicon Valley, to Washington DC, getting help from President Barack Obama, and what business leaders can do to actively change racial injustice.Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Building a business means making mistakes. Lots of them. But how you’re wrong isn’t always obvious. Jack Conte has learned this lesson as a working musician — and while scaling Patreon into a company worth $4b. In Part One of a two-part series, you’ll hear how Jack wrote his own Wrongness Playbook, as he learned to answer questions like: If something isn’t working, is it time to trust your instincts? Or is there critical feedback you’ve been ignoring? Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Amazon wants to get bigger, but with that scale comes great responsibility. So says Adam Selipsky, CEO of Amazon Web Services, the most profitable and fastest growing part of the tech giant. Selipsky, who also oversees Amazon’s climate change efforts, points to two additions to the company’s vaunted “Leadership Principles” as evidence of Amazon’s commitment. Arguing that AWS is still in early days, he shares what he’s hearing from other CEOs about their biggest concerns, why “carbon intensity” is the best measure of climate progress for businesses, and what Amazon's aspiration to be “Earth’s best employer” really means. Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How can small businesses survive in times of volatility? How should an entrepreneur balance limited resources with big ambitions? Reid Hoffman and Bob Safian answer questions from small business owners in the Masters of Scale community. Plus: another round of Pivot Point, and a Need to Know segment.Learn more about becoming a Masters of Scale Member: www.mastersofscale.com/membersRead a transcript of Strategy Session 13 at https://mastersofscale.com/strategy-session-13-how-to-build-trust-in-a-brand-new-space/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Eric Schmidt, former CEO of Google, breaks down his deep insights around artificial intelligence on Rapid Response. Schmidt, co-author of the book "The Age of AI: And Our Human Future," alongside Dr. Henry Kissinger and MIT’s Daniel Huttenlocher, says that we’re entering an unknown era with technology – one that requires extra vigilance to ensure that we amplify the positives and de-amplify the negatives. His advice to businesses: You need to be running as fast as you can toward AI applications. If your competitor gets there first, you'll be in trouble. Schmidt argues that AI will change business, society, and potentially humanity itself. "It's important that our systems not enable the worst of us, but instead promote the best of us,” he says.Read the book "The Age of AI: And Our Human Future" from Henry Kissinger, Eric Schmidt, and Daniel Huttenlocher: https://www.barnesandnoble.com/w/the-age-of-ai-henry-a-kissinger/1139558876?ean=9780316273800Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Creative energy is the raw fuel of entrepreneurship, but if you fail to direct that energy effectively, you risk chasing multiple ideas and delivering none. Tony Fadell learned this lesson time and again through his journey to co-create the iPod, iPhone, and Nest. He shares how he struck the tricky balance of channeling his creative experimentation into world-changing products.Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.