🇺🇸 United States Episodes

In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance. We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins. Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Craig Koniver 00:04:52 Sponsors: Joovv & BetterHelp 00:07:40 What is a Peptide? 00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health 00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation 00:18:43 BPC-157, Inflammation 00:23:27 BPC-157, Injection & Oral Forms; Injury Repair 00:28:43 Sourcing, Anabolic Steroids, Testosterone 00:34:48 Black & Gray Market, Compounding Pharmacies, Purity 00:38:20 Sponsor: AG1 00:39:51 Partnering with a Physician, LPS 00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses 00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone 00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides 00:58:45 Sponsor: Function & Eight Sleep 01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health 01:05:16 Prescriptions, Physicians & Trust 01:14:09 Agency in Your Health 01:17:13 MK-677, Appetite 01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing 01:21:10 Methylated B Vitamins, Homocysteine 01:24:47 Peptides for Sleep, Pinealon, Epitalon 01:31:03 Glycine, Liver Detoxification; Dosage 01:37:19 GLP-1, Compounding Pharmacies 01:39:03 Stem Cell Therapy, PRP 01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health 01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses 01:50:20 Covid, NAD Infusion, NMN & NR Supplements 01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR 02:07:53 PT-141, Vyleesi, Libido; Nausea 02:10:57 FDA Approval & Removal, Pharmaceutical Companies 02:20:17 Positivity, Mindset & Health 02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

On this week’s episode of Farm Camp: Gillian Anderson! Chicago, computers, industrial films, pornography, and evolution. Do you believe in aliens? It’s an all-new SmartLess.

Will Tennyson is a YouTuber and an athlete. Taking a journey from fat to fit is a massive achievement in itself. Will then went on to become one of the best creators of positive fitness and mindset content on the internet and today we get to discover some of his best lessons from a decade of self-improvement. Expect to learn why Will decided to become morbidly obese for a day and what he learned, which diet allowed him to lose the most weight, his thoughts on the state of male body dysmorphia, what Will thinks of Nikocado Avocado’s insane transformation, what Will's mental health journey looks like and much more... Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get expert bloodwork analysis and bypass Function’s 300,000-person waitlist at https://functionhealth.com/modernwisdom (automatically applied at checkout) Get 5 Free Travel Packs, Free Liquid Vitamin D and more from AG1 at https://drinkag1.com/modernwisdom (automatically applied at checkout) Enroll in Hillsdale College's free online courses at https://hillsdale.edu/modernwisdom (automatically applied at checkout) Get 10% discount on all Gymshark’s products at https://gym.sh/modernwisdom (use code MW10) Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

Aman Sanger, Arvid Lunnemark, Michael Truell, and Sualeh Asif are creators of Cursor, a popular code editor that specializes in AI-assisted programming. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep447-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/cursor-team-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Cursor Website: https://cursor.com Cursor on X: https://x.com/cursor_ai Anysphere Website: https://anysphere.inc/ Aman's X: https://x.com/amanrsanger Aman's Website: https://amansanger.com/ Arvid's X: https://x.com/ArVID220u Arvid's Website: https://arvid.xyz/ Michael's Website: https://mntruell.com/ Michael's LinkedIn: https://bit.ly/3zIDkPN Sualeh's X: https://x.com/sualehasif996 Sualeh's Website: https://sualehasif.me/ SPONSORS: To support this podcast, check out our sponsors & get discounts: Encord: AI tooling for annotation & data management. Go to https://encord.com/lex MasterClass: Online classes from world-class experts. Go to https://masterclass.com/lexpod Shopify: Sell stuff online. Go to https://shopify.com/lex NetSuite: Business management software. Go to http://netsuite.com/lex AG1: All-in-one daily nutrition drinks. Go to https://drinkag1.com/lex OUTLINE: (00:00) - Introduction (09:25) - Code editor basics (11:35) - GitHub Copilot (18:53) - Cursor (25:20) - Cursor Tab (31:35) - Code diff (39:46) - ML details (45:20) - GPT vs Claude (51:54) - Prompt engineering (59:20) - AI agents (1:13:18) - Running code in background (1:17:57) - Debugging (1:23:25) - Dangerous code (1:34:35) - Branching file systems (1:37:47) - Scaling challenges (1:51:58) - Context (1:57:05) - OpenAI o1 (2:08:27) - Synthetic data (2:12:14) - RLHF vs RLAIF (2:14:01) - Fields Medal for AI (2:16:43) - Scaling laws (2:25:32) - The future of programming PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

Meet Liberato Kani, a hip hop artist in Lima, Peru—or as he says, “the Andean Bronx”. At his concerts, a typical call and response you hear is "Quechua es resistencia": Quechua is resistance. Though Quechua is spoken by nearly ten million people, Peru's native language is at risk of dying off because of anti-indigenous prejudice. Liberato and other musicians like Renata Flores are here to save it—and restore a country's pride while they're at it. Want to talk more about the show? Share your favorite artist from this episode with host Saleem Reshamwala (@Kidethnic) on Twitter. This episode features music and interviews from Liberato Kani, Renata Flores, Kayfex, and Uchpa's guitarist and songwriter Marcos Maizel. Listen to more from these artists on TED's Spotify playlist, "Quechua es Resistencia.”Pindrop is produced by Jesse Baker and Eric Nuzum of Magnificent Noise for TED. Our production staff includes Elyse Blennerhassett, Oscar Durand, Kim Nederveen Pieterse, Sabrina Farhi, Hiwote Getaneh, Angela Cheng, and Michelle Quint, with the guidance of Roxanne Hai Lash and Colin Helms. Additional recordings by Whitney Henry-Lester and Hernando Suarez. Translation and transcription by Hernando Suárez, Eilis O’Neill, and Oscar Durand. This episode was mixed and sound designed by Kristin Mueller. For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

How do you come back from being “canceled”? Are we more likely to forgive someone if they cry? And what makes a successful public apology?

Animal behavior expert Philip Johns introduces us to the vibrant urban environments of Singapore, where city dwellers and skyscrapers coexist with a rich array of other species, including otters, hornbills and lizards — prompting the question: Can we design cities to be wildlife refuges?For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Derek Sivers is an entrepreneur, author, and speaker. Things are not what they are, things are what we think they are. The power of reframing and changing your perspective is a kind of alchemy, and today we get to hear some of Derek's best principles for altering the way you see everything. Expect to learn how you can reframe your perspective for the better, what the term ‘Useful Not True’ means, why your thoughts cannot be trusted, why people don’t bond over facts but rather perspectives, how to not become discouraged if you are thrown off course, how to make better decisions and much more... Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a 20% discount on the best supplements from Momentous at https://livemomentous.com/modernwisdom (automatically applied at checkout) Get a Free Sample Pack of all LMNT Flavours with your first box at https://drinklmnt.com/modernwisdom (automatically applied at checkout) Get $150 discount on Plunge’s amazing sauna or cold plunge at https://plunge.com (use code MW150) Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

The lawyer commercial is almost an art form unto itself. Learned practitioners of the law doing whatever it takes to get your attention, from impressive dirt bike stunts to running around half naked. All so when you land in trouble, you don't have to think hard to remember their name. Odds are you can name one or two right now.This world of law ads did not exist fifty years ago. Then, lawyers were not allowed to advertise. Not by law, by the exclusive organization that decides who gets to be a lawyer: state bars.On today's episode, how that changed. How a couple of lawyers placing an ad in a local newspaper led to the inescapable world of law firm ads we know today. And, how the right to advertise got put on the same level as some of the most important, fundamental rights we have.This episode was hosted by Nick Fountain and Jeff Guo. It was produced by Sam Yellowhorse Kesler with help from Sean Saldana. It was edited by Jess Jiang. It was fact-checked by Sierra Juarez and engineered by Valentina Rodríguez Sánchez. Alex Goldmark is Planet Money's executive producer.Help support Planet Money and hear our bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

The point of mass immigration is to destroy your culture. It’s an act of war against you. Respond accordingly. (0:27) Take Back Wisconsin (12:13) They Want to Erase Your Culture (22:18) Creepy Tim Walz (32:18) Q&A (32:55) How Do We Fight Back? (55:15) How Do We Instill Hope in the Next Generation? (1:03:28) Is Trump Going to Win? (1:10:57) The Importance of Voting (1:18:05) How Do We Preserve Liberty? Learn more about your ad choices. Visit megaphone.fm/adchoices

Last month, Microsoft and Constellation Energy announced a deal to restart Pennsylvania’s Three Mile Island, the site of the country’s worst nuclear power accident. WSJ’s Jennifer Hiller reports that the goal is to power the tech giant’s growing artificial intelligence ambitions. Further Listening: - Artificial: The OpenAI Story  - Microsoft CEO Satya Nadella's Big Bet on AI  Further Reading: - Three Mile Island’s Nuclear Plant to Reopen, Help Power Microsoft’s AI Centers  Learn more about your ad choices. Visit megaphone.fm/adchoices

What we eat is less about what we choose and more about what’s offered to us, says food and climate expert Sarah Lake. Unpacking how governments and companies have driven up meat consumption in the US through extensive marketing, she explains how we could employ these same forces to incentivize plant-based eating — for the sake of the planet, public health and global food security.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Episode 635: Sam Parr ( https://x.com/theSamParr ) and Shaan Puri ( https://x.com/ShaanVP ) talk about the things Shaan learned while at Re-convene in Los Angeles.  — Show Notes:  (0:00) the low-status-technique for becoming high-status at a conference (7:09) the richer the guy, the weirder the guy (12:17) dressing well vs. dressing comfortably (18:25) meeting mike posner (26:06) little luxuries  — Check Out Shaan's Stuff: Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam’s List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

The vice-presidential candidates took center stage at a debate this week. Ryan Knutson talks with Molly Ball about the important takeaways, and Rachel Humphreys speaks to a listener about why she’s thinking about climate change this election.  Further Listening: - Red, White and Who? Playlist  - Red, White and Who? It's Always the Economy!  - Red, White and Who? Why Ohio Could Decide the Senate  Further Reading: - JD Vance’s Version of Trump Is Better Than the Real Thing  Learn more about your ad choices. Visit megaphone.fm/adchoices

“In the United States, we have 50 laboratories of democracy and they're called states.”

(0:00) The Besties intro Mark Cuban: Voting record, working with Ross Perot's campaign in 1992 (5:43) The history of Cuban's love/hate relationship with Trump (19:08) Trump's performance as President: what he got right and wrong (40:46) Party nominations: Kamala vs. Trump (49:18) Biden's performance as President: what he got right and wrong (55:45) Should Kamala share blame for Biden's failures? (1:07:01) International conflict, national debt, crypto regulation (1:21:33) General sense of Kamala Harris, why she's been avoiding adversarial interviews, why Sacks supports Trump (1:31:47) Selling a majority of his Mavericks stake, changing business landscape of the NBA, what he's working on at Cost Plus Drugs (1:44:50) Thoughts on AI, what's next for him (1:51:37) Relationship with Elon, re-evaluating the Twitter deal, OpenAI's new fundraise Follow Mark: https://x.com/mcuban Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect Referenced in the show: https://www.eia.gov/dnav/pet/hist/LeafHandler.ashx?n=pet&s=mcrfpus2&f=m https://fred.stlouisfed.org/series/GFDEBTN https://www.architecturaldigest.com/story/wait-are-windowless-bedrooms-going-to-be-a-thing https://washingtonreporter.news/editorial/scoop-kamala-harris-likely-to-nominate-gary-gensler-as-treasury-secretary-if-elected-senate-sources

When are negative emotions enjoyable? Are we all a little masochistic? And do pigs like hot sauce?

Under CEO John Donahoe, Nike pulled away from retailers and ramped up production of its classic sneaker lines. Now sales have plummeted, the company has lost market share to competitors and Donahoe is stepping down. WSJ's Inti Pacheco discusses what went wrong. Further Reading: -Nike CEO John Donahoe Stepping Down After Rocky Tenure  -How Nike Missed the Boom in Running Culture  -Nike Reverses Course as Innovation Stalls and Rivals Gain Ground  Further Listening: -Nike’s Sneaky Sneaker Thieves  -How Allbirds Lost Its Footing  Learn more about your ad choices. Visit megaphone.fm/adchoices

With all that spam clogging your inbox, a more personalized experience with the brands you interact with would be a refreshing change of pace. Sharing insights from his research into what brands can do to improve the experience of the people they want to reach, personalization pioneer Mark Abraham highlights a key mindset that can help companies boost their growth (and delight their customers) in the era of AI.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Do Harris and Walz support infanticide? The media claim they don’t. Charlie Camosy is a medical ethicist who trains physicians. He knows for a fact they do.  (0:47) Why Are Democrats Promoting Infanticide? (16:59) Who’s Funding This Mass Infanticide? (23:59) Something Is Shifting in the Pro-Life Movement (32:30) Brain Death (1:01:32) Organ Harvesting (1:20:54) There Is a Massive Revival Happening (1:28:33) Porn Addiction (1:44:13) The Corruption of Medical Ethicists (1:53:30) Why Are Our Politicians Anti-Reproduction? Paid partnerships: ExpressVPN: Get 3 months free at https://ExpressVPN.com/Tucker PreBorn: Save babies and souls. Go to https://PreBorn.com/Tucker Learn more about your ad choices. Visit megaphone.fm/adchoices