🇺🇸 United States Episodes

Innovation is crucial for game-changing advancements in society, whether it's treatments for serious diseases, developments in AI technology, or rocket science.Today on the show, we're airing two episodes from our daily economics show The Indicator. First, a new paper suggests that breakthrough innovations are more likely at smaller, younger companies. We talk to an inventor who left a big pharmaceutical company to start afresh, leading to some incredible treatments for serious diseases.Then, it's off to Mars — or at least, on the way. Elon Musk's company SpaceX did a first test launch of a rocket meant to go all the way to the red planet. The rocket made it up off of the launch pad and lumbered briefly through the sky before self-destructing over the Gulf of Mexico. Suffice it to say, it's not quite ready. NPR science correspondent Geoff Brumfiel walks us through SpaceX's business plan as we try to figure out if this company has the funding and business acumen to reach its moonshot goal.These two Indicator episodes were originally produced by Corey Bridges & Brittany Cronin, engineered by Katherine Silva & James Willets, and fact-checked by Dylan Sloan & Sierra Juarez. Kate Concannon edits the show.The Planet Money version of this episode was produced by Willa Rubin, engineered by Robert Rodriguez, and edited by Keith Romer.Help support Planet Money and get bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

The Covenant of Water is a six-part Super Soul podcast series hosted by Oprah Winfrey in conversation with bestselling author Dr. Abraham Verghese. The series explores all 10 parts of his acclaimed novel: family secrets, romance, spirituality, medical mysteries and the resilience of the human spirit. Oprah and Dr. Verghese share their own experiences to offer insights into the book. Launches June 21st. New Episodes Every Wednesday. Learn more here: https://www.oprah.com/sp/the-covenant-of-water-companion-podcast.html Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Full Transcript and show notes: https://www.latent.space/p/function-agents?sd=pfTimestamps:[00:00:00] Intro[00:01:47] Recapping June 2023 Updates[00:06:24] Known Issues with Long Context[00:08:00] New Functions API[00:10:45] Riley Goodside[00:12:28] Simon Willison[00:14:30] Eric Elliott[00:16:05] Functions API and Agents[00:18:25] Functions API vs Google Vertex JSON[00:21:32] From English back to Code[00:26:14] Embedding Price Drop and Pinecone Perspective[00:30:39] Xenova and Huggingface Perspective[00:34:23] Function Selection[00:39:58] Designing Code Agents with Function API[00:42:16] Models as Routers[00:46:48] Prompt Engineering replaced by Finetuning[00:52:15] The 2 Code x LLM Paradigms[00:56:30] Smol Models for the future[00:58:54] The Evolution of the GPT API[01:03:27] Functions API Security vs Prompt Injection[01:16:18] GPT Model Upgrades[01:17:36] JSONformer[01:21:03] Closing Comments - What We Want Next Get full access to Latent.Space at www.latent.space/subscribe

Ali Siddiq is a stand-up comic, writer, and public speaker. His new special, "The Domino Effect II: Loss," is available now on YouTube. www.alisiddiq.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Who runs the world? Political scientist Ian Bremmer argues it's not as simple as it used to be. With some eye-opening questions about the nature of leadership, he asks us to consider the impact of the evolving global order and our choices as participants in the future of democracy.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

The holy grail of company building is finding product-market fit. But what most people don’t tell you is that once you’ve found it, product-market fit brings its own set of challenges, particularly when it comes to scaling rapidly and hiring the right executives at the right time. Drawing from their extensive experiences, a16z cofounder Ben Horowitz and Databricks cofounder and CEO Ali Ghodsi sit down to talk about the hardest things about executive hiring and firing, and what is at stake. They dive into the common reasons an exec fails, why sometimes micromanagement is a good idea, and the difference between someone who has written a playbook and someone who has only run one.

Original Air Date: February 13th, 2019 Award-winning actor and producer Michael B. Jordan discusses his skyrocketing career and why he says his life has already "exceeded his dreams.” Michael’s breakout performance came in 2013’s “Fruitvale Station,” directed by visionary Ryan Coogler. The duo teamed up again for the “Rocky” sequel, “Creed,” and then for the mega-blockbuster “Black Panther,” which was nominated for an Academy Award for Best Picture. Michael says after playing superhero villain Erik Killmonger in “Black Panther,” he went to therapy. “As a man, I think we get a lot of slack for … what it is to be masculine,” he says. “I don’t really subscribe to that because I feel like everybody needs to unpack and talk, whether it’s with a therapist or a close friend or family member.” Want more podcasts from OWN? Visit https://bit.ly/OWNPods You can also watch Oprah’s Super Soul, The Oprah Winfrey Show and more of your favorite OWN shows on your TV! Visit https://bit.ly/find_OWN

Matthew McConaughey is an Oscar-winning actor and author of Greenlights. Please support this podcast by checking out our sponsors: – Riverside: http://creators.riverside.fm/LEX and use code LEX to get 30% off – MasterClass: https://masterclass.com/lex to get 15% off – AG1: https://drinkag1.com/lex to get 1 year of Vitamin D and 5 free travel packs EPISODE LINKS: Matthew’s Twitter: https://twitter.com/McConaughey Matthew’s Instagram: https://instagram.com/officiallymcconaughey/ Matthew’s YouTube: https://youtube.com/@MatthewMcConaughey Greenlights (book): https://greenlights.com/ Roadtrip (course): https://artoflivinevent.com/roadtrip PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (05:57) – Relationships (10:44) – Dreams (22:56) – Fear of death (34:40) – Overcoming pain (57:45) – Amazon rainforest (1:04:29) – AI (1:17:45) – Truth (1:25:50) – Ego (1:33:34) – Dallas Buyers Club (1:40:03) – True Detective (1:48:49) – Yellowstone (1:53:51) – Texas (1:55:43) – Politics (2:00:29) – Interstellar (2:03:26) – Aliens (2:10:23) – Advice for young people (2:18:42) – Meaning of life

Cameron Hanes is a master bowhunter, outdoorsman, elite athlete, author, and host of the podcast “Keep Hammering with Cameron Hanes.” www.cameronhanes.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

In between two songs that showcase her raw vocal powers, singer-songwriter Jessie Reyez delivers an inspiring talk about how she's turned wins into losses -- and reminds us we're all capable of magic. (This talk contains mature language.)Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Breaking new ground, Think Fast, Talk Smart steps into the world of live events, bringing together an eager audience of LEAD students from Stanford University and a top-notch panel of former podcast guests: Jesper B. Sørensen, Sarah Soule, Jonathan Levav,and Szu-chi Huang. Topics include crafting strategy for successful leadership and tips on how to effectively lead a hybrid team.This episode also features an interactive audience segment, where various participants of the Stanford LEAD program answer the three questions traditionally posed to guests.Connect:Premium Signup >>>> Think Fast Talk Smart PremiumEmail Questions & Feedback >>> [email protected] Transcripts >>> Think Fast Talk Smart WebsiteNewsletter Signup + English Language Learning >>> FasterSmarter.ioThink Fast Talk Smart >>> LinkedIn,  Instagram, YouTubeMatt Abrahams >>> LinkedIn ********Thank you to our sponsors.  These partnerships support the ongoing production of the podcast, allowing us to bring it to you at no cost.Strawberry.me. Get 50% off your first coaching session today at Strawberry.me/smartJoin our Think Fast Talk Smart Learning Community and become the communicator you want to be. 

It's easy to see how big stresses at work or home -- like layoffs, illnesses, or even a complex and important project -- cause anxiety too spike. But sometimes the stresses that cause the most hard are the tiny, everyday ones that build up over time into a much bigger problem because we don't take the time to recognize and manage our reactions to them. Former HBR editor Karen Dillon and Babson College professor Rob Cross studied the most common types of "microstress" and the ways in which they impact individuals, teams, and organizations. They explain why, if left unchecked, microstress can lead to mistakes, burnout, damaged relationships, and poor mental and physical health. But they also offer advice for better handling it -- and helping others to do the same. Dillon and Cross wrote the book The Microstress Effect and the HBR article "The Hidden Toll of Microstress."

* Try Shepherd Out - https://www.supportshepherd.com/ * Shaan's Personal Assistant System - http://shaanpuri.com/remoteassistant Episode 464: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk about the Reddit revolt, the Turpentine network of business and technology podcasts, and how Shaan invested his Milk Road money. Want to see more MFM? Subscribe to the MFM YouTube channel here. Check Out Shaan's Stuff: * Power Writing Course * Daily Newsletter Check Out Sam's Stuff: * Hampton * Ideation Bootcamp * Copy That ----- Show Notes: (00:50) - Reddit Revolt (30:00) - Turpentine (41:15) - What Shaan did with his Milk Road money (47:00) - Shaan’s newest acquisition ------ Links: * Reddark * Spezless * Turpentine * Aging Media Network * Shepherd * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. ------ Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

To achieve true cultural impact, follow authentic storytelling and spot untapped consumer needs. Recorded live at the Masters of Scale Summit in San Francisco, filmmaker and entrepreneur Tyler Perry and Netflix’s co-CEO Ted Sarandos talk with host Reid Hoffman about redefining culture, evaluating the playing field, and ignoring conventional wisdom. Sarandos explains how scaling the personal touch of curation and taking risks evolved Netflix into a streaming juggernaut. Perry shares insights about the importance of ownership and how creating his own seat at the table spawned the largest film production company in the U.S.Read a transcript of this episode: https://mastersofscale.com/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My guest this week is Scott Goodwin. Scott is the co-founder and managing partner of Diameter Capital Partners, which he started as a credit hedge fund in 2017 and has expanded into a $13 billion investment firm that covers all credit markets. Scott spent the first 8 years of his career at Citi where he rose to head of High Yield Trading before moving to Anchorage Capital in 2010 where he led their global trading desk. Scott is one of my favorite examples of the joke I used to make about this show, when I said it should be called - "This is who you're up against." He's one of the sharpest investors I know and I'm sure you'll see why. Please enjoy my great discussion with Scott Goodwin. Founders Podcast Founders Episode 136 - Estee Lauder Founders Episode 288 - Ralph Lauren For the full show notes, transcript, and links to mentioned content, check out the episode page here. ----- This episode is brought to you by Tegus. Tegus is the modern research platform for leading investors, and provider of Canalyst. Tired of calculating fully-diluted shares outstanding? Access every publicly-reported datapoint and industry-specific KPI through their database of over 4,000 driveable global models handbuilt by a team of sector-focused analysts, 35+ industry comp sheets, and Excel add-ins that let you use their industry-leading data in your own spreadsheets. Tegus’ models automatically update each quarter, including hard to calculate KPIs like stock-based compensation and organic growth rates, empowering investors to bypass the friction of sourcing, building and updating models. Make efficiency your competitive advantage and take back your time today. As a listener, you can trial Canalyst by Tegus for free by visiting tegus.co/patrick. ----- Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.  Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more. Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here. Follow us on Twitter: @patrick_oshag | @JoinColossus Show Notes (00:03:07) - (First question) - Comparing the investing themes of the ‘10s to the ‘20s (00:04:59) - The skillset differences between investing in equity versus credit  (00:06:28) - Why Carvana’s stock plummeted and thoughts on the destruction of value (00:07:33) - General overview of credit cycles and what they are   (00:15:42) - Opportunities come from knowing the names well enough  (00:19:17) - Making substantial decisions in a matter of minutes as a credit investor  (00:22:23) - How he thinks about the evolution of sourcing alpha in credit markets (00:27:37) - Why so many institutional capital pools have fewer credit managers   (00:31:08) - His childhood and the unique aspects of it that set him apart (00:37:28) - Lessons learned early on about running an investment firm (00:43:34) - The role imagination plays in credit investing (00:46:35) - How weekly breakfasts lead to an investing partnership (00:50:51) - What Tracy Fenton has done for Diameter (00:53:05) - Things that should change about investing firms writ large (00:57:09) - Calling balls and strikes and how his team learns and works together (00:59:37) - Why he’s motivated more by failure than success (01:00:54) - Where he finds the most joy in his investing process (01:04:07) - Non-negotiable attributes he’d look for when investing in other GPs (01:05:22) - New variables that have his attention in the current market (01:08:27) - What feels like unfinished business to him (01:09:43) - His reaction to everything going on today in real estate (01:10:52) - The kindest thing anyone has ever done for him

Uber CEO Dara Khosrowshahi dropped by the Acquired studio for an Eats delivery, so we broke out the cameras and asked him to hang out for a wide-ranging conversation. :) We talk about his 20 years working with Barry Diller, starting his career at Allen & Company, how the Uber CEO search process ACTUALLY went down… and oh yeah, the massive transformation that’s happened at Uber over the past few years. When Dara took over the company it was bleeding huge sums of cash, losing share to competitors and embroiled in one of the biggest corporate controversies in recent memory. Fast forward to today and it’s turned cashflow positive while also having tripled revenue to over $30B (on $120B in GMV) and solidified its rideshare dominance in the US. And in perhaps the biggest change, it’s done it all while staying out of the headlines. Tune in!LinksBen & David on My First MillionSponsors:Sierra: https://bit.ly/acquiredsierraSentry: https://bit.ly/acquiredsentryAnthropic: https://bit.ly/acquiredclaude25Vanta: https://vanta.com/acquired More Acquired!Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCNote: Acquired hosts and guests may hold assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. You should do your own research and make your own independent decisions when considering any financial transactions.

Louis meets singer, songwriter and DJ Craig David. Craig discusses his life and career, including how the TV series Bo Selecta affected his career, the benefits of celibacy and what it was like living in a hotel at Heathrow Terminal 5. Warnings: Contains strong language and sensitive themes. Links: Craig David Presents TS5 / KISS Ibiza https://www.youtube.com/watch?v=X13UhVt7UMs  Craig David Album – Born TO Do It https://open.spotify.com/album/5TedEgCbtmvDnXzUtXEFJY?si=W8F2Qu_6RF2fZlcVnFksaA TS5 Craig David Soundcloud https://soundcloud.com/ts5official Bo Selecta Albert Hall https://www.youtube.com/watch?v=nVDo3Z9c5SY Donnie Osmond – Puppy Love https://open.spotify.com/track/7HWH4kGaHR3ZwKNFPT4dSW?si=f50fb581093d4c2a The Ebony Rockers https://www.youtube.com/watch?v=odscATxcvsE Craig David book https://www.amazon.co.uk/Whats-Your-Vibe-Tuning-into/dp/1529109728 Craig David – What's Your Flava? https://open.spotify.com/track/2keZJNufsIqgoO6w58bNGK?si=870a39c98c8f4ee5   Credits:  Producer: Paul Kobrak  Assistant Producer: Maan Al-Yasiri  Production Manager: Francesca Bassett  Music: Miguel D’Oliveira  Show notes compiled by Shaloma Ellis  Executive Producer: Arron Fellows     A Mindhouse Production exclusively for Spotify  www.mindhouse.co.uk   Learn more about your ad choices. Visit podcastchoices.com/adchoices

Nearly half of all pregnancies in the United States are unplanned, the result of millions of people being unable to get the birth control method that works best for them. Reproductive health advocate and 2023 Audacious Project grantee Mark Edwards discusses Upstream USA's nationwide effort to expand access to high-quality contraceptive care by integrating it into primary health-care settings -- a crucial shift towards increasing equal health opportunities and empowering people to decide when and if they want to start families. (This ambitious idea is a part of the Audacious Project, TED's initiative to inspire and fund global change.)Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

In this episode, I discuss Methyl​enedioxy​methamphetamine (MDMA), which is also commonly known as “ecstasy” or “molly,” including how it works in the brain to cause short- and long- term-shifts in emotional processing and its clinical applications for the treatment of post-traumatic stress disorder (PTSD), alcohol and other substance-use addictions. I discuss the neuronal mechanisms for how MDMA elevates mood, empathy, motivation, social engagement, and reduces “threat detection” and how these effects can synergistically support talk therapy. I also explain the ongoing debate about the potential neurotoxicity of MDMA, myths about the origins and treatments for post-MDMA “crash,” the evolving legal landscape around MDMA use for clinical purposes, and I caution recreational users about the extremely dangerous additives (e.g., fentanyl) now commonly found in black market MDMA. This should be of interest to those curious about MDMA, neuropharmacology, the origins of emotional processing in the brain, empathy, PTSD, neuroplasticity, mental health and psychiatry. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) MDMA “Ecstasy” (00:04:54) Sponsors: LMNT & Waking Up (00:08:18) MDMA History & Synthesis; Legality (00:14:45) MDMA, Methamphetamine (Meth), Dopamine & Serotonin (00:23:30) MDMA vs Psychedelics vs Ketamine (00:26:54) MDMA & Serotonin 1B Receptor, Subjective Feelings, Trauma (00:30:12) Sponsor: AG1 (00:34:51) Amygdala & Threat Detection, Pro-Social Behavior, MDMA Dosages (00:45:48) Interoception, MDMA & Post-Traumatic Stress Disorder (PTSD) (00:52:36) Long-Term Effects, Threat Detection & PTSD (00:56:14) MDMA, Social Connection & Empathy; Meth, SSRIs (01:07:22) Oxytocin & MDMA (01:16:10) Safety & Neurotoxicity; Recreational Use, Caffeine & Fentanyl (01:26:36) Is MDMA Neurotoxic?; Poly-Pharmacology, Body Temperature (01:37:07) Post-MDMA “Crash”, Prolactin & P‑5‑P (01:43:07) PTSD & Trauma; Talk Therapy, SSRIs (01:54:09) PTSD Treatment: Talk Therapy + MDMA (02:02:46) MDMA & Addiction; Dissociative PTSD & Empathy (02:09:47) Side-Effects?, MDMA Efficacy & Legality (02:15:22) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

Pull over and turn the car off— it’s “the ultimate Daddy” a.k.a. Pedro Pascal, stuck in an empty interrogation room with us. This week includes a Pinochet quiz, a Xerox industrial commercial, numerous lavender helmet wipes, and just a whole lotta’ rizz. Come join our cult; it’s SmartLess. Please support us by supporting our sponsors.