🇺🇸 United States Episodes

With @jorgecondebio @vijaypande and @lr_bio On this special holiday weekend edition of the a16z bio Journal Club we discuss a recent opinion article suggesting the end of Eroom’s Law—the decades long trend in biopharma R&D towards higher and higher costs per new drug—and our take on the big trends in this space.

Joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion. This episode includes: Abhishek Kumar Maurya, the founder of UberPro.In; the companies capitalizing on people fleeing cities; how tech is helping humans become fitter; the world of alternate data; the Freeport for baseball cards; and the million dollar challenge.  See acast.com/privacy for privacy and opt-out information.

Adam Hart is a scientist, author & presenter. Our species has been around for far longer than the modern world. This is leading to some imbalances between our evolutionary heritage and the environment we now find ourselves in. Expect to learn how obesity might be an evolutionary adaptation gone awry, why fight or flight happens in the workplace, the misalignment of technology with our brains, the evolutionary basis for violence and much more... Sponsor: Shop Eleiko’s full range at https://www.shop.eleiko.com (enter code MW15 for 15% off everything) Extra Stuff: Buy Unfit For Purpose - https://amzn.to/2ZlMFa1  Follow Professor Hart on Twitter - https://twitter.com/AdamHartScience Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact Learn more about your ad choices. Visit megaphone.fm/adchoices

Matt Botvinick is the Director of Neuroscience Research at DeepMind. He is a brilliant cross-disciplinary mind navigating effortlessly between cognitive psychology, computational neuroscience, and artificial intelligence. Support this podcast by supporting these sponsors: - The Jordan Harbinger Show: https://www.jordanharbinger.com/lex - Magic Spoon: https://magicspoon.com/lex and use code LEX at checkout If you would like to get more information about this podcast go to https://lexfridman.com/ai or connect with @lexfridman on Twitter, LinkedIn, Facebook, Medium, or YouTube where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on Apple Podcasts, follow on Spotify, or support it on Patreon. Here's the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time. OUTLINE: 00:00 - Introduction 03:29 - How much of the brain do we understand? 14:26 - Psychology 22:53 - The paradox of the human brain 32:23 - Cognition is a function of the environment 39:34 - Prefrontal cortex 53:27 - Information processing in the brain 1:00:11 - Meta-reinforcement learning 1:15:18 - Dopamine 1:19:01 - Neuroscience and AI research 1:23:37 - Human side of AI 1:39:56 - Dopamine and reinforcement learning 1:53:07 - Can we create an AI that a human can love?

The coronavirus brought much of the world to a standstill, dropping carbon emissions by five percent. Al Gore says keeping those rates down is now up to us. In this illuminating interview, he discusses how the steadily declining cost of wind and solar energy will transform manufacturing, transportation and agriculture, offer a cheaper alternative to fossil fuels and nuclear energy and create millions of new jobs. Stay tuned for a lively debate about geoengineering and hear Gore's thoughts about how humanity can create a clean, prosperous future through a focused global effort and a generation of young people committed to change. (This virtual conversation, hosted by head of TED Chris Anderson, was recorded June 23, 2020.)For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion. The guys discuss: Andrew Wilkinson Hey.com replacer, VidIQ for influencers, why Grammarly is a huge business, learning via text messages and Stadium Live (ESPN for Gen Z).  See acast.com/privacy for privacy and opt-out information.

Russell Peters is an actor and stand up comedian. His latest stand up special "Deported" is now available on Amazon Prime. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Where leaders should and shouldn’t focus their attention.

At the crossroads of life and livelihood, scholar D-L Stewart invites us into scenes from his own life as he resists and reflects on the dehumanizing narratives that shape the Black trans experience in the US. With each word of his captivating and poetic dissection, Stewart emphasizes the magnitude and urgency of the rallying cry "Black trans lives matter" -- and calls on others to uphold that truth, too.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

"This was like 1918, 1929 and 1968 in one week," says Darren Walker, president of the Ford Foundation. With the pandemic, economic crisis, and civil unrest all coming together after George Floyd's death, Walker found himself flooded with calls from CEOs struggling for how to respond. Walker's advice mixes clear-eyed messages — denying the trauma borne by communities of color is no longer option — with optimism about the opportunities ahead. At the Ford Foundation, they've accelerated giving and even exceeded their own KPIs. With more leaders dedicated to making a positive impact, he says, the wind is changing, for people of color and for America. Interviewed by editor Bob Safian.Read a transcript of this episode at https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter at https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode was originally recorded on Ben's show Ben Coomber Radio. I enjoyed this discussion about alcohol and drinking habits so much, I figured I'd put it on Modern Wisdom too. Lots more talking by me on this one, which you might enjoy. As bars & pubs reopen after lockdown, it's a crucial time to remind yourself of being intentional & deliberate with your drinking. Rather than restarting a weekend warrior lifestyle, now could be a great opportunity to reset your routine & habits around alcohol. Enjoy this discussion, big thanks to Ben for letting me use the episode. Sponsor: Get Surfshark VPN at https://surfshark.deals/MODERNWISDOM (Enter promo code MODERNWISDOM for 85% off and 3 Months Free) Extra Stuff: Take a break from alcohol and upgrade your life - https://6monthssober.com/podcast Check out Ben's Podcast - https://bencoomber.com/pages/ben-coomber-radio Check out Ben's supplement company - https://awesomesupplements.co.uk/ Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact Learn more about your ad choices. Visit megaphone.fm/adchoices

James Lindsay is an author, mathematician, and political commentator. His latest book, co-authored with Helen Pluckrose, Cynical Theories: How Activist Scholarship Made Everything about Race, Gender, and Identity―and Why This Harms Everybody will be available on August 25, 2020. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Around the world, Indigenous food cultures vanish because of industrialized agriculture and a shifting, Western-influenced concept of the ideal diet. Food researcher Aparna Pallavi explores why once-essential culinary traditions disappear from people's lives and memories almost without notice -- and serves up a subtle solution to revitalize our connection to the foods we eat.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

Joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion. Episode summary: (5:15) The unbundling of Reddit (11:50) The formula for finding niches to unbundle (16:24) Examples of a subreddits that could become a business (31:00) The businesses that use giveaways to grow.  See acast.com/privacy for privacy and opt-out information.

Oprah Winfrey visits Academy Award-winning actress Jane Fonda and her adopted African-American daughter Mary Williams for their first-ever interview together. They discuss how they met and Mary shares what it was like becoming a part of Jane's larger-than-life world. Jane's biological son Troy also joins the conversation, discussing what it was like to have Mary come into their family. Later, Oprah and Jane speak one-on-one about the importance of giving back to the world, love and motherhood.

Barbara Freese is an author, environmental attorney and a former Minnesota assistant attorney general. Her latest book Industrial-Strength Denial is now available: https://www.ucpress.edu/book/9780520296282/industrial-strength-denial Learn more about your ad choices. Visit podcastchoices.com/adchoices

Robert Langer is a professor at MIT and one of the most cited researchers in history, specializing in biotechnology fields of drug delivery systems and tissue engineering. He has bridged theory and practice by being a key member and driving force in launching many successful biotech companies out of MIT. Support this podcast by supporting these sponsors: - MasterClass: https://masterclass.com/lex - Cash App – use code "LexPodcast" and download: - Cash App (App Store): https://apple.co/2sPrUHe - Cash App (Google Play): https://bit.ly/2MlvP5w This conversation is part of the Artificial Intelligence podcast. If you would like to get more information about this podcast go to https://lexfridman.com/ai or connect with @lexfridman on Twitter, LinkedIn, Facebook, Medium, or YouTube where you can watch the video versions of these conversations. If you enjoy the podcast, please rate it 5 stars on Apple Podcasts, follow on Spotify, or support it on Patreon. Here's the outline of the episode. On some podcast players you should be able to click the timestamp to jump to that time. OUTLINE: 00:00 - Introduction 03:07 - Magic and science 05:34 - Memorable rejection 08:35 - How to come up with big ideas in science 13:27 - How to make a new drug 22:38 - Drug delivery 28:22 - Tissue engineering 35:22 - Beautiful idea in bioengineering 38:16 - Patenting process 42:21 - What does it take to build a successful startup? 46:18 - Mentoring students 50:54 - Funding 58:08 - Cookies 59:41 - What are you most proud of?

"Life doesn't go from A to B -- it's messy," says sailing legend Tracy Edwards. In this inspiring talk, she tells how she went from teenage misfit to skipper of the first all-female crew in the toughest race on the seas -- and how she now helps young people around the world achieve their dreams, too.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

With @trvrb @heyjudka and @lr_bio We speak with Trevor Bedford, Associate Professor at the Fred Hutchinson Cancer Research Center, about a wide-range of topics, including changes in scientific communication and publishing spurred by the COVID-19 pandemic, the power of genomic epidemiology for tracking the evolution of outbreaks, how this information can aid public health decisions, and preparing for and preventing the next pandemic.

Carlos Brito, the CEO of Anheuser-Busch InBev since 2008, has worked to build a culture of adaptability and customer centricity at the global brewer. Many of his leadership principles are paying off during the Covid-19 pandemic, as empowered employees have quickly changed course to respond to the crisis. Brito explains the challenges his company faces in a making beer for social gatherings at a time when people need to stay apart for safety, how the company has shifted operations and supply chains thanks in part to early lessons in markets such as China and South Korea, and how he’s leading strategic efforts to position AB InBev for a new reality.