Managing a crisis is more than a communications challenge -- it's a business challenge and an opportunity to change your culture. a16z's Margit Wennmachers and Kim Milosevich discuss crisis communications 101.

With the field of synthetic biology -- which involves designing and engineering organisms to specific purposes -- exploding and driving both innovation and real-world impact from drug development to manufacturing and more, how did we get here? This episode digs deep with one of the pioneers of the synbio field.

With increased demand for better batteries, cobalt has become one of the most important metals on the planet. Kobold Metals co-founder and CEO Kurt House, John Thompson of Cornell, and a16z general partner Connie Chan join Hanne Winarsky in discussing why this happened and how technology is rapidly changing the age-old mining industry.

While new generative AI models like DALL-E 2 and Imagen have recently brought broader awareness and excitement to the space, AI is already changing how we work and the software we use across the enterprise. People.AI founder and CEO Oleg Rogynskyy and a16z partner Peter Lauten discuss, in this episode from 2019.

In times of great uncertainty, it can help to examine the longer arc of innovation and where we are headed. MIT economist and best-selling author Andrew McAfee joins Marc Andreessen and Sonal Choksi to discuss the case for why human progress and growth doesn't have to be in conflict with preserving our environment and resources.

In this crossover episode from new show "web3 with a16z", a16z general partners Chris Dixon and Ali Yahya and a16z crypto head of research Tim Roughgarden, with host Sonal Choksi, set context and discuss the connections between blockchain, crypto, and web3, as well as how lessons from earlier eras of the web do and don't apply to the current moment.

In this special “innovation overview” episode from April 2021, the a16z crypto team and other experts give a primer on crypto and web3, starting from the basics of crypto and how it works to more recent innovations and beyond -- all through the lens of an oral essay.

The story of startups is often a story of survival. What do you do when the markets go down? When your biggest customer churns? When your big product launch falls flat? Ben Horowitz and Jason Rosenthal share stories and lessons learned from doing whatever they could to help their companies survive in hard times.

What can today’s startups learn from Amazon’s so-called “invention machine” and a culture of growth and innovation that led to several successful and diverse lines of products? As it scaled, how did Amazon define and adapt its culture and practices to promote innovation even as it got more complex and large? Longtime Amazon execs Colin Bryar and Bill Carr take us behind-the-scenes.

In turbulent times, it's critical to to understand the fundamental finances that drive the business. One of the key metrics both investors and founders look at is gross margins. This conversation digs into the what, when, and why gross margins matter for both early and late stage startups.

Every founder's journey is unique, and a16z general partner David Ulevitch's is no exception. From working in tech during the Dot Com boom to founding and guiding his own startups to successful exits to becoming an investor, he shares his story with The Modern CTO's Joel Beasley. But while every journey is different, some of the lessons remain the same.

What was it like to build and demo new things for Steve Jobs? How did Apple develop the software components of iconic hardware products iPhone, iPad, and more? Longtime Apple software engineer and designer Ken Kocienda shares stories and lessons from his career at Apple with a16z's Frank Chen.

“Disruption” is a word often used in the tech -- and yet, spotting and harnessing truly disruptive technology is much trickier than it looks. Benedict Evans and Steven Sinofsky use the example of Tesla and electric vehicles to dig into the nuances of what disruption looks like in practice, in the tech industry and beyond.

Netflix CEO and co-founder Reed Hastings talks with a16z co-founder Ben Horowitz about his management philosophies and learnings from managing Netflix through multiple pivots. Because as companies grow and their technologies and customers rapidly evolve, building a resilient culture that can reinvent the product and itself is critical for enduring success.

So, you’ve found product market fit and you’re starting to acquire users. But it’s not enough to just have users – you need to make sure they’re sticking around and keep finding value in your product. How do you measure and track user engagement and retention? a16z general partners Andrew Chen (formerly of Uber and author of the book, The Cold Start Problem) and Jeff Jordan (formerly of OpenTable, eBay) dig into the two key elements for any growth strategy: engagement and retention.

Growth is one of the most top of mind questions for entrepreneurs building startups of all kinds -- but how does one go beyond a mindset of "growth hacking" to thinking about growth more systemically and holistically? a16z general partners Andrew Chen (formerly of Uber and author of the book, The Cold Start Problem) and Jeff Jordan (formerly of OpenTable, eBay) dig into the fundamentals of growth, starting with user acquisition.

Over a decade after the idea of “big data'' was first born, data has become the central nervous system for decision-making in organizations of all sizes. But the modern data stack is evolving and which infrastructure trends and technologies will ultimately win out remains to be decided. Five leaders in data infrastructure debate the future of the modern data stack.

In the face of great uncertainty, how do you make decisions? Can you really apply the lessons of the past to the present and the future, to navigate seemingly new situations and get what you want out of business and life? Ray Dalio, co-chief investment office at Bridgewater Associates and author of several books, including "Principles: Life and Work", digs deep into these questions with a16z's Alex Rampell and Sonal Chokshi.

With Web3 gathering more momentum than ever before across the tech ecosystem, what can we learn from the recent past of tech adoption? In this episode from December 2018, author and podcaster Brian McCullough talks with a16z general partner Chris Dixon about the origins of the internet, based on Brian’s book, How the Internet Happened: From Netscape to the iPhone.

with @vpostrel @smc90 In this deep dive conversation about The Fabric of Civilization: How Textiles Made the World, we cover everything from science and math across several fields; to commerce to management & measurement; to the always-meta narrative of HOW innovation happens…