Dmitri Dolgov is the CTO of Waymo, an autonomous vehicle company. Please support this podcast by checking out our sponsors: – Tryolabs: https://tryolabs.com/lex – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – BetterHelp: https://betterhelp.com/lex to get 10% off – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Waymo’s Twitter: https://twitter.com/waymo Waymo’s Website: https://waymo.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:46) – Computer games (12:52) – Childhood (15:24) – Robotics (16:14) – Moscow Institute of Physics and Technology (18:26) – DARPA Urban Challenge (28:46) – Waymo origin story (44:27) – Waymo self-driving hardware (53:00) – Connected cars (58:53) – Waymo fully driverless service in Phoenix (1:03:14) – Getting feedback from riders (1:11:28) – Creating a product that people love (1:17:18) – Do self-driving cars need to break the rules like humans do? (1:24:03) – Waymo Trucks (1:29:41) – Future of Waymo (1:42:53) – Role of lidar in autonomous driving (1:55:53) – Machine learning is essential for autonomous driving (1:59:55) – Pedestrians (2:06:32) – Trolley problem (2:11:00) – Book recommendations (2:22:26) – Meaning of life

Michael Mina is an immunologist, epidemiologist, and physician at Harvard. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Michael’s Twitter: https://twitter.com/michaelmina_lab Michael’s Time article: https://time.com/5912705/covid-19-stop-spread-christmas/ Rapid Tests: https://www.rapidtests.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:28) – Interacting between viruses and bacteria (11:42) – Deadlier viruses (15:13) – Will COVID-19 mutate? (16:47) – Rapid testing (34:11) – PCR vs rapid antigen tests (43:55) – Medical industrial complex (47:47) – Lex takes COVID test (54:32) – FDA and cheap tests (57:17) – Explanation of Elon Musk’s positive COVID tests (1:04:25) – Role of testing during vaccine deployment (1:07:54) – Public health policy (1:17:34) – A weather system for viruses (1:34:26) – Can a virus kill all humans? (1:40:05) – Engineering a deadly virus (1:44:47) – AlphaFold 2 and viruses (1:50:42) – Advice for young people (1:58:50) – Time as a Buddhist monk (2:04:54) – Meditation (2:12:32) – Meaning of life

Matthew W. Johnson is a professor and psychedelics researcher at Johns Hopkins. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Neuro: https://www.getneuro.com and use code LEX to get 15% off – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Matt’s Twitter: https://twitter.com/Drug_Researcher Matt’s Website: https://www.hopkinsmedicine.org/profiles/results/directory/profile/0800020/matthew-johnson Study Website: https://hopkinspsychedelic.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:31) – Introduction to psychedelics (22:33) – Psychedelics expand the mind (25:44) – The priors we bring to the psychedelic experience (29:40) – Elon Musk and first principles thinking (40:10) – DMT (51:32) – Joe Rogan and DMT (57:40) – The nature of drug addiction (1:11:29) – The economics of drug pricing (1:17:44) – Should we legalize all drugs? (1:29:46) – What is the most dangerous drug? (1:32:20) – Does drug prohibition work? (1:36:14) – Cocaine and sex (1:43:15) – Risky sexual decisions (1:54:12) – Psilocybin helping people quit smoking (2:00:30) – Young Jamie (2:22:38) – Participating in a study (2:29:57) – Psychedelics and the human mind (2:37:20) – The future of psychedelics (2:40:01) – Neuralink (2:49:33) – Consciousness (3:02:15) – Panpsychism (3:12:20) – Aliens and DMT (3:22:24) – Mortality (3:32:12) – Meaning of life

Michael Littman is a computer scientist at Brown University. Please support this podcast by checking out our sponsors: – SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – MasterClass: https://masterclass.com/lex to get 2 for price of 1 – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Michael’s Twitter: https://twitter.com/mlittmancs Michael’s Website: https://www.littmania.com/ Michael’s YouTube: https://www.youtube.com/user/mlittman PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:43) – Robot and Frank (10:02) – Music (13:13) – Starring in a TurboTax commercial (23:26) – Existential risks of AI (41:48) – Reinforcement learning (1:07:36) – AlphaGo and David Silver (1:17:15) – Will neural networks achieve AGI? (1:29:42) – Bitter Lesson (1:42:32) – Does driving require a theory of mind? (1:51:58) – Book Recommendations (1:57:20) – Meaning of life

John Clarke is a BJJ black belt and MMA coach. Please support this podcast by checking out our sponsors: – Theragun: https://theragun.com/lex to get 30 day trial – Magic Spoon: https://magicspoon.com/lex and use code LEX to get free shipping – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get $200 off – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Broadway Jiu Jitsu website: https://www.broadwayjiujitsu.com Broadway Jiu Jitsu instagram: https://www.instagram.com/broadwayjiujitsu Please, Allow Me podcast: https://podcasts.apple.com/us/podcast/please-allow-me/id1531735873 Please, Allow Me instagram: https://www.instagram.com/please_allow_me_podcast/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:25) – The great American road trip (25:54) – Martial arts and philosophy (28:55) – Real vs fake success on Instagram (39:40) – The brutal honesty of Mike Tyson (44:26) – Breaking your opponent in wrestling (52:32) – Genghis Khan (1:03:38) – It’s okay to change your mind (1:08:15) – Why do politicians become inauthentic (1:14:52) – Greatness requires sacrifice (1:17:36) – Whiplash (1:25:44) – Relationships (1:31:21) – Greatest fighters of all time (1:39:02) – Greatest fight of all time (1:53:25) – Khabib Nurmagomedov (1:55:13) – Can Conor McGregor beat Khabib Nurmagomedov? (2:09:29) – Conor vs Khabib 2 (2:16:05) – Will there always be war? (2:17:41) – Future of civilization (2:19:52) – Kids (2:26:37) – The meaning of a “like” on social media (2:35:34) – Starting a podcast (2:54:16) – Book recommendations (2:57:46) – Keeping the independence of solitude

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors: – Grammarly: https://grammarly.com/lex to get 20% off premium – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Manolis Website: http://web.mit.edu/manoli/ Manolis Twitter: https://twitter.com/manoliskellis Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:48) – Music and life (46:21) – The number 42 (52:22) – The question about the meaning of life (55:02) – Are humans unique in the universe? (1:00:46) – Human civilization (1:12:52) – Mars (1:14:45) – Human mind and the abstraction layers of reality (1:25:38) – Neural networks and intelligence (1:32:55) – Ideas as organisms (1:42:19) – Language (1:53:34) – Legacy (2:08:25) – Poems SONGS MENTIONED: [1] Dwros Gewrgiadis – An imoun plousios https://www.youtube.com/watch?v=7akZoEQv6jI [2] Grigoris Bithikotsis – Ftoxologia https://www.youtube.com/watch?v=TyGR24O0KQ8 [3] Sto perigiali to kryfo https://www.youtube.com/watch?v=B-GBPx_GXQw [4] Michael Jackson – Man in the Mirror https://www.youtube.com/watch?v=Zqe5NP86OCc [5] George Michael – Careless Whisper https://www.youtube.com/watch?v=izGwDsrQ1eQ [6] Gainsbourg with Isabelle Adjani – Pull Marine https://www.youtube.com/watch?v=o7MwHGHWgLk [7] Georges Moustaki – Le meteque https://www.youtube.com/watch?v=MV8fGf-N06A [8] Jacques Brel – Ne me quitte pas https://www.youtube.com/watch?v=q_bq5mStroM [9] Sting – Englishman In New York https://www.youtube.com/watch?v=d27gTrPPAyk [10] Sting – Fragile https://www.youtube.com/watch?v=lB6a-iD6ZOY [11] Pink Floyd – The Wall (When the Tigers Broke Free) https://www.youtube.com/watch?v=l9b9UhFe6Eg [12] Pink Floyd – The Wall (One Of My Turns) https://www.youtube.com/watch?v=BOay-7aqLks [13] Sting – Russians https://www.youtube.com/watch?v=wHylQRVN2Qs [14] Joni Mitchell – Both sides now https://www.youtube.com/watch?v=aCnf46boC3I [15] Leonard Cohen – I’m Your Man https://www.youtube.com/watch?v=yOnXe8ttmjY [16] Alison Krauss & Union Station – The Lucky One https://www.youtube.com/watch?v=jcRZ_J_VgNc

Erik Brynjolfsson is an economist at Stanford. Please support this podcast by checking out our sponsors: – Vincero: https://vincerowatches.com/lex to get up to 25% off + free shipping – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Erik’s Twitter: https://twitter.com/erikbryn Erik’s Website: https://www.brynjolfsson.com/ The Second Machine Age (book): https://amzn.to/33f1Pk2 Machine, Platform, Crowd (book): https://amzn.to/3miJZ76 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:23) – Exponential growth (12:51) – Elon Musk exponential thinking (15:08) – Moore’s law is a series of revolutions (20:31) – GPT-3 (22:09) – Autonomous vehicles (29:11) – Electricity (33:40) – Productivity (38:47) – Why is Twitter and Facebook free? (49:03) – Dismantling the nature of truth (52:24) – Nutpicking and Cancel Culture (58:39) – How will AI change our world (1:04:40) – Existential threats (1:06:33) – AI and the nature of work (1:12:39) – Thoughts on Andrew Yang and UBI (1:18:30) – Economics of innovation (1:24:37) – Effect of COVID on the economy (1:33:50) – MIT and Stanford (1:38:23) – Book recommendations (1:41:28) – Meaning of life

Lisa Feldman Barrett is a neuroscientist, psychologist, and author. Please support this podcast by checking out our sponsors: – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get $200 off – MasterClass: https://masterclass.com/lex to get 15% off annual sub – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Seven and a Half Lessons About the Brain (book): https://amzn.to/2Sp5ar9 How Emotions Are Made (book): https://amzn.to/2GwAFg6 Lisa’s Twitter: https://twitter.com/LFeldmanBarrett Lisa’s Website: https://lisafeldmanbarrett.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:27) – Falling in love (25:10) – Love at first sight (39:49) – Romantic (43:48) – Writing process (54:32) – Evolution of the human brain (1:08:41) – Nature of evil (1:17:23) – Love is an evolutionary advantage (1:21:59) – Variation in species (1:27:41) – Does evolution have a direction? (1:45:19) – Love with an inanimate object (1:49:37) – Just be yourself is confusing advice (1:59:49) – Consciousness (2:06:26) – Book recommendations

Andrew Huberman is a neuroscientist at Stanford. Please support this podcast by checking out our sponsors: – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get $200 off – SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Andrew’s Instagram: https://www.instagram.com/hubermanlab Andrew’s Wikipedia: https://en.wikipedia.org/wiki/Andrew_D._Huberman Andrew’s Website: http://www.hubermanlab.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:24) – Fear (14:36) – Virtual reality (18:20) – Claustrophobia (20:08) – Skydiving (21:43) – Overcoming fears (26:43) – Optimal performance (29:57) – Deep work (45:22) – Psychedelics (49:08) – Deep work (1:02:48) – Everything in the brain is an abstraction (1:10:06) – Human vision system (1:21:42) – Neuralink (1:49:12) – Science of consciousness (2:04:00) – David Goggins (2:21:04) – Science communication (2:28:36) – Man’s Search for Meaning

Yaron Brook is a objectivist philosopher, podcaster, and author. Please support this podcast by checking out our sponsors: – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Yaron’s Twitter: https://twitter.com/yaronbrook Yaron Brook Show (YouTube): https://www.youtube.com/user/ybrook Free Market Revolution (book): https://amzn.to/32H0oLb Equal is Unfair (book): https://amzn.to/32K3NsC PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:28) – Principles of a life well lived (14:35) – Free will (20:50) – Nature of reality (29:28) – Ayn Rand (1:01:11) – Objectivism (1:26:29) – Godel Incompleteness Theorem (1:31:36) – Capitalism (2:01:22) – Virtue of selfishness (2:11:27) – Win-win (2:17:31) – Anarchy (2:36:24) – Tribalism and division (2:40:42) – Objectivism and Jordan Peterson on personal responsibility

Alex Filippenko is an astrophysicist and professor of astronomy at Berkeley. Please support this podcast by checking out our sponsors: – Neuro: https://www.getneuro.com and use code LEX to get 15% off – BetterHelp: https://betterhelp.com/lex to get 10% off – MasterClass: https://masterclass.com/lex to get 15% off annual sub – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Alex’s Website: https://astro.berkeley.edu/people/alex-filippenko/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:36) – Universe expansion (08:00) – Dark energy (15:28) – Scientific revolutions (27:18) – Asteroid hitting Earth (30:50) – Giant solar flares and the power grid (37:50) – Elon Musk and space exploration (42:41) – Exoplanets (50:03) – Traveling close to the speed of light (52:13) – Traveling faster than the speed of light (1:00:39) – Intelligent life in the universe (1:04:14) – Fermi Paradox (1:13:52) – Finding alien life would be bad news (1:18:49) – UFO sightings (1:31:58) – Universe expansion speed (1:36:42) – The universe is infinite (1:40:58) – What happened before the Big Bang? (1:45:14) – Roger Penrose (1:48:48) – Nobel Prize for the accelerating universe (2:10:23) – Supernova (2:21:47) – The greatest story ever told (2:25:44) – Richard Feynman (2:32:37) – Meaning of life

Dan Carlin is a historian, political thinker, and podcaster. Please support this podcast by checking out our sponsors: – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get free vitamin D – SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera – Magic Spoon: https://magicspoon.com/lex and use code LEX to get free shipping – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Dan’s Twitter: https://twitter.com/hardcorehistory Dan’s Website: https://www.dancarlin.com/ Hardcore History podcast: https://apple.co/2HX7hAA Common Sense podcast: https://apple.co/3mM6WPZ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:53) – Nature of evil (14:50) – Is violence and force fundamental to human civilization? (19:58) – Will we always have war? (29:38) – The Russian front in World War II (37:32) – Ideologies of the US, the Soviet Union, and China (50:15) – Putin (1:02:50) – Journalism is broken (1:10:16) – Genghis Khan (1:24:36) – Greatest leader in history (1:32:21) – Could Hitler have been stopped? (1:49:21) – Hitler’s Antisemitism (1:55:12) – Destructive power of evil (2:04:26) – Will human civilization destroy itself? (2:16:31) – Elon Musk, Tesla, SpaceX (2:24:53) – Steering around the iceberg – wow do we avoid collapse of society? (2:47:00) – Advice on podcasting (2:50:12) – Joe Rogan, Spotify, and the future of podcasting (3:05:19) – Future episodes of Hardcore History podcast (3:20:21) – Is Ben real? (3:21:05) – Meaning of life

Charles Isbell is the Dean of the College of Computing at Georgia Tech. Please support this podcast by checking out our sponsors: – Neuro: https://www.getneuro.com and use code LEX to get 15% off – Decoding Digital: https://appdirect.com/decoding-digital – MasterClass: https://masterclass.com/lex to get 15% off annual sub – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Charles’s Twitter: https://twitter.com/isbellHFh Charles’s Website: https://www.cc.gatech.edu/~isbell/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:16) – Top 3 movies of all time (13:26) – People are easily predictable (19:08) – Breaking out of our bubbles (30:54) – Interactive AI (37:26) – Lifelong machine learning (45:53) – Faculty hiring (53:27) – University rankings (1:00:55) – Science communicators (1:10:20) – Hip hop (1:19:20) – Funk (1:20:44) – Computing (1:36:35) – Race (1:52:40) – Cop story (2:01:01) – Racial tensions (2:10:23) – MLK vs Malcolm X (2:13:44) – Will human civilization destroy itself? (2:18:14) – Fear of death and the passing of time

Eric Weinstein is a mathematical physicist, podcaster, and intellectual. Please support this podcast by checking out our sponsors: – Grammarly: https://grammarly.com/lex to get 20% off premium – Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off – SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Eric’s Twitter: https://twitter.com/EricRWeinstein Eric’s YouTube: https://www.youtube.com/ericweinsteinphd The Portal podcast: https://podcasts.apple.com/us/podcast/the-portal/id1469999563 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 07:46 – Eddie Van Halen 15:26 – Leonard Cohen 23:22 – Battle between ego and humility 28:38 – Darkness and beauty 35:20 – Jimi Hendrix 38:08 – Good Will Hunting 42:16 – Revolutionary minds 53:49 – Next Elon Musk should come from MIT 58:14 – Love with save the world 1:03:30 – Are we headed toward a civil war? 1:15:04 – Joe Rogan 1:28:52 – Our political leaders 1:34:11 – Younger people should have more power 1:44:30 – The Portal 2:09:20 – Money 2:11:26 – Roger Penrose 2:19:06 – Jeffrey Epstein 2:37:44 – We need to get off this planet 2:40:41 – An update on Geometric Unity 2:46:33 – Gratitude

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors: – SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru – Pessimists Archive: https://pessimists.co/ – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get $200 off – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Manolis Website: http://web.mit.edu/manoli/ Manolis Twitter: https://twitter.com/manoliskellis Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 08:05 – Molecular basis for human disease 32:04 – Deadliest diseases 37:47 – Genetic component of diseases 46:38 – Genetic understanding of disease 1:02:25 – Unified theory of human disease 1:08:26 – Genome circuitry 1:33:29 – CRISPR 1:45:06 – Mitochondria 1:53:10 – Future of biology research 2:22:46 – The genetic circuitry of disease

George Hotz (geohot) is a programmer, hacker, and the founder of Comma.ai. Please support this podcast by checking out our sponsors: – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 40% & free shipping – Decoding Digital: https://appdirect.com/decoding-digital – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Comma.ai’s Twitter: https://twitter.com/comma_ai Comma.ai’s Website: https://comma.ai/ George’s Instagram: https://www.instagram.com/georgehotz George’s Twitch: https://www.twitch.tv/georgehotz George’s Twitter: https://twitter.com/realgeorgehotz Comma.ai YouTube (unofficial): https://www.youtube.com/channel/UCwgKmJM4ZJQRJ-U5NjvR2dg PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 07:02 – Will human civilization destroy itself? 09:49 – Where are the aliens? 14:36 – Tic Tac UFO and Bob Lazar 17:04 – Conspiracy theories 19:07 – The programming language of life 23:28 – The games that humans play 31:58 – Memory leaks in the simulation 34:29 – Theories of everything 36:14 – Ethereum startup story 44:02 – Cryptocurrency 53:28 – Self-help advice 57:08 – Comma.ai 59:02 – Comma two 1:07:50 – Tesla vs Comma.ai 1:16:53 – Driver monitoring 1:30:34 – Communicating uncertainty 1:32:22 – Tesla Dojo 1:38:50 – Tesla Autopilot big rewrite 1:45:09 – How to install the Comma Two 1:49:44 – Openpilot is Android & Autopilot is iOS 1:58:59 – Waymo 2:10:12 – Autonomous driving and society 2:12:24 – Moving 2:15:29 – Advice to Startups 2:28:32 – Programming setup 2:31:32 – Ideas that changed my life 2:39:37 – GPT-3 2:42:57 – AGI 2:47:00 – Programming languages that everyone should learn 2:53:33 – How to learn anything 2:56:05 – Book recommendations 3:04:28 – Love 3:06:17 – Psychedelics 3:08:38 – Crazy

Chris Lattner is a world-class software & hardware engineer, leading projects at Apple, Tesla, Google, and SiFive. Please support this podcast by checking out our sponsors: – Blinkist: https://blinkist.com/lex and use code LEX to get a free week of premium – Neuro: https://www.getneuro.com and use code LEX to get 15% off – MasterClass: https://masterclass.com/lex to get 15% off annual sub – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Chris’s Twitter: https://twitter.com/clattner_llvm Chris’s Website: http://nondot.org/sabre/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 07:12 – Working with Elon Musk, Steve Jobs, Jeff Dean 12:42 – Why do programming languages matter? 18:42 – Python vs Swift 29:35 – Design decisions 34:53 – Types 38:41 – Programming languages are a bicycle for the mind 41:13 – Picking what language to learn 47:12 – Most beautiful feature of a programming language 56:36 – Walrus operator 1:06:03 – LLVM 1:11:15 – MLIR compiler framework 1:15:21 – SiFive semiconductor design 1:27:56 – Moore’s Law 1:31:09 – Parallelization 1:35:37 – Swift concurrency manifesto 1:46:26 – Running a neural network fast 1:52:03 – Is the universe a quantum computer? 1:57:44 – Effects of the pandemic on society 2:14:56 – GPT-3 2:19:15 – Software 2.0 2:32:41 – Advice for young people 2:37:24 – Meaning of life

Scott Aaronson is a quantum computer scientist. Please support this podcast by checking out our sponsors: – SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get $200 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – BetterHelp: https://betterhelp.com/lex and use code LEX to get 10% off EPISODE LINKS: Scott’s Blog: https://www.scottaaronson.com/blog/ Our previous episode: https://www.youtube.com/watch?v=uX5t8EivCaM PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 07:46 – Simulation 12:38 – Theories of everything 18:18 – Consciousness 40:32 – Roger Penrose on consciousness 50:44 – Turing test 54:31 – GPT-3 1:03:02 – Universality of computation 1:09:33 – Complexity 1:15:38 – P vs NP 1:27:57 – Complexity of quantum computation 1:40:03 – Pandemic 1:53:49 – Love

Lisa Feldman Barrett is a neuroscientist, psychologist, and author. Please support this podcast by checking out our sponsors: – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get free vitamin D3/K2 – Magic Spoon: https://magicspoon.com/lex and use code LEX to get free shipping – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Seven and a Half Lessons About the Brain (book): https://amzn.to/2Sp5ar9 How Emotions Are Made (book): https://amzn.to/2GwAFg6 Lisa’s Twitter: https://twitter.com/LFeldmanBarrett Lisa’s Website: https://lisafeldmanbarrett.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 06:35 – Are we alone in the universe? 08:03 – Life on Earth 12:55 – Collective intelligence of human brains 21:43 – Triune brain 27:52 – The predicting brain 35:48 – How the brain evolved 41:47 – Free will 50:40 – Is anything real? 1:03:13 – Dreams 1:09:00 – Emotions are human-constructed concepts 1:34:29 – Are women more emotional than men? 1:43:05 – Empathy 2:14:46 – Love 2:18:40 – Mortality 2:20:16 – Meaning of life

Michael Malice is a political thinker, podcaster, and author. Please support this podcast by checking out our sponsors: – SEMrush: https://www.semrush.com/partner/lex/ to get a free month of Guru – DoorDash: https://doordash.com/ and use code LEX to get $5 off – MasterClass: https://masterclass.com/lex to get 15% off annual sub EPISODE LINKS: Michael’s Twitter: https://twitter.com/michaelmalice Michael’s Community: https://malice.locals.com/ Michael’s YouTube: https://www.youtube.com/channel/UC5tj5QCpJKIl-KIa4Gib5Xw Michael’s Website: http://michaelmalice.com/about/ Your Welcome podcast: https://bit.ly/30q8oz1 The New Right (book): https://amzn.to/34gxLo3 Dear Reader (book): https://amzn.to/2HPPlHS PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 – Introduction 04:15 – Sponsors 07:58 – Putin and the Russian soul 15:01 – Love and trolling 25:31 – Problem with government 31:03 – Anarchism 53:07 – Politics 54:59 – Are most people capable of thinking deeply? 1:02:08 – Willy Wonka and Albert Camus view of life 1:08:08 – Trolling 1:12:26 – Conspiracy theories 1:29:43 – Donald Trump and the Election 1:36:58 – Trump Biden presidential debates 1:41:15 – Journalism is broken 1:47:56 – Communism 1:54:02 – Presidential candidates 2:04:34 – Libertarian party 2:14:56 – Objectivism 2:24:17 – Trolling 2:35:21 – The New Right 2:43:29 – Cancel culture 3:13:17 – Book recommendations 3:18:08 – Fear of mortality 3:21:08 – Meaning of life