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The fever of the compounded weight-loss pens

From 🇧🇷 O Assunto, published at 2025-12-02 03:16

Guests: Bruno Geloneze, endocrinologist and researcher at Unicamp, and Henderson Fürst, director of the Brazilian Society of Bioethics. Last week, a Federal Police operation targeted an illegal scheme for producing pens used for weight loss. In Brazil, only one laboratory is authorized to sell Tirzepatide (the active ingredient in Mounjaro) on a large scale. However, the medicine can be compounded in pharmacies, allowing doctors to adjust the exact dose for patients with specific needs. In the scheme investigated by the Federal Police, the doctor produced Tirzepatide on a large scale, without following the rules established by Anvisa. The high demand for compounded weight-loss pens has an explanation: for this type of medication, the price can be half the value of the original drugs, whose patents are held by large manufacturers. In this episode, Victor Boyadjian speaks with endocrinologist Bruno Geloneze and lawyer Henderson Fürst. An expert in endocrinology and metabolic diseases and a researcher at Unicamp's Center for Research in Obesity and Comorbidities, Geloneze explains the differences between laboratory-made and compounded medications. He details the risks of using weight-loss pens without knowing their exact origin and is emphatic: what's cheap can turn out to be expensive. Henderson, director of the Brazilian Society of Bioethics, discusses how a judgment by the Superior Court of Justice (STJ) in the coming weeks could change the patent status of weight-loss pens in Brazil. Former president of the OAB Bioethics Commission, Henderson talks about the impacts of ending patents for this type of medication and explains which Anvisa rules for the production and consumption of the pens are currently in force.

Is Saudi Arabia recreating the greatest transformation stories in history?

From 🇸🇦 سقراط مع عمر الجريسي, published at 2025-12-02 03:00

What is the link between Japan's economic miracle and Saudi Vision 2030? A question that reveals two similarities separated by half a century, yet united by a single passion. In this episode, we host Mohammed Al-Meshekah, Co-founder and CEO of Outliers Financial, to understand with him the points of similarity between the two stories, what made the Japanese experience a globally inspiring model, and how Saudi Arabia is currently forging its own path towards a modern economic renaissance. We talk about how venture capital has become a key driver of growth and innovation in Saudi Arabia today, and a lever that opens the door for companies that are shaping the future and reshaping the economy. Al-Meshekah says: We are living in an exceptional period for creating institutions that lead not only regionally but also globally! We delve deeper into investments and venture capital funds: how do they work? Why does Al-Meshekah see opportunities in them rather than in global companies? And what are his criteria for selecting companies to invest in? • Opportunity for those interested: The Socrates team is looking for passionate individuals to work with. If interested, apply via the link. • Follow football news and its contexts in real-time in the newsletter “Informed Source” • The New Square is a gateway to another world.

The backyard of fast fashion

From 🇮🇱 אחד ביום (Echad Ba'Yom), published at 2025-12-02 03:00

In recent years, November has become the biggest shopping month, and most packages arriving in the country are full of clothes. These are clothes that mostly come from fast fashion websites – whose products may contain dangerous chemicals, and which belong to one of the most polluting industries in the world. So this time, we'll take a peek into the backyard of the fashion world and try to understand how we got to this situation. Guests: Maayan Prati, consumer reporter for Channel 12 News, and Dr. Meital Peleg Mizrachi, fashion and climate researcher, postdoctoral fellow in the Department of Economics at Yale University.

Introducing: The Rest Is Science

From 🇬🇧 The Rest Is Politics, published at 2025-12-02 00:00

Forget what you think you know about reality. The Rest Is Science is a mind-bending new show from Goalhanger that tears down familiar ideas… time, randomness, beauty, it will reveal just how bizarre the world truly is. Join Professor Hannah Fry and science creator Michael Stevens (aka Vsauce) twice a week to explore big, small and surprising questions as they deep dive into theories, concepts, objects and thoughts and take us on a journey into the unexpected. If you love digging into details that usually get skipped over, this is the show that proves reality is stranger than fiction. Click here to subscribe to The Rest Is Science. Learn more about your ad choices. Visit podcastchoices.com/adchoices

19 - TiP ToP

From 🇰🇪 The 97s Podcast, published at 2025-12-01 22:36

WaGwan MDAu!!

Pope Leo XIV concluded his historic visit to Turkey and departed for Lebanon

From 🇦🇷 Cara o Ceca, published at 2025-12-01 21:23

Pope Leo XIV concluded his historic visit to Turkey and departed for Lebanon. During his last day in Istanbul, the Pontiff was received by Ecumenical Patriarch Bartholomew I, with whom he had signed the previous day a joint declaration in favor of peace in the Middle East and in support of strengthening ties between Catholics and Orthodox. "This tour was planned by Francis and follows the path of peace amidst conflicts such as Ukraine, Sudan, the Middle East. Leo is a voice in the wilderness calling for peace and disarmament," said Fortunato Malimaci, a researcher specializing in religion, on Cara o Ceca.

Inside Quince’s Quest to Sell Luxury Goods for Less

From 🇺🇸 The Journal, published at 2025-12-01 21:05

Quince is seemingly everywhere. Since launching in 2018, the brand has built an e-commerce empire that brings in $1.1 billion annually, and has catapulted to the top of the "dupe" economy. But the company’s strategy of making its own versions of best-selling products has run into some pushback from competitors. WSJ’s Chavie Lieber takes us inside Quince’s strategy and ensuing legal battles. Jessica Mendoza hosts. Further Listening: - Smucker, Trader Joe's and a Battle Over PB&Js - Why Is Everyone Obsessed With Labubus? - How Target Got Off Target Sign up for WSJ’s free What’s News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

The mosquito of December 1, 2025

From 🇮🇹 La Zanzara, published at 2025-12-01 20:45

The Mosquito of December 1, 2025

John Rich on Diddy, Demons, the Antichrist, How to Hear God, and His War on Child Predators

From 🇺🇸 The Tucker Carlson Show, published at 2025-12-01 19:15

John Rich on the moral cowardice of some American Christians. Don’t run from evil; confront it. (00:00) The Moment John Rich Realized What's Actually Important In Life (06:02) The Universal Language of Music (10:34) The Dark Side of the Music Industry (40:02) John's Work With DHS to Take Down Child Predators (55:03) Is John Worried About His Career If He Continues to Preach the Gospel? Paid partnership with: Poncho Outdoors: Go to https://PonchoOutdoors.com/Tucker and enter your email for $10 off your first order. Audien Hearing: Visit https://HearTucker.com or call 1-800-453-2916 to learn more about how Audien can help you or someone you love hear better. Hallow prayer app: Get 3 months free at https://Hallow.com/Tucker TCN: Shop the kind of Christmas gifts people won’t re-gift at https://store.tuckercarlson.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Prof. Marcin Majewski. Which party would Jesus belong to today?

From 🇵🇱 WojewódzkiKędzierski, published at 2025-12-01 19:00

In this episode, we ask about everything that is usually not appropriate to discuss in religion class: would Jesus have TikTok and a party membership card today? Was he an effective politician of his time? Was he Lucifer? We wonder if the Bible is an instruction manual for modernity, or rather a mirror of our need to order chaos. We ask if Adam "Nergal" Darski is also a child of God, and if the number 666 is an omen or a literary game. We return to the "Our Father" as a Jewish prayer, look at women in ancient texts, St. Paul... and also his possible sexual orientation. This is an episode where the Bible becomes a series full of twists like "Breaking Bad", and Prof. Majewski removes layers of interpretive dust from it, showing it as a living, literary, and surprisingly humorous text. Do we rightly contest the figure of Judas? Or perhaps he wasn't a traitor at all? And finally: when will the end of the world be? Is it still worth buying third-party liability and comprehensive insurance?

NDPP Appointment to shape SA Business landscape as Bitcoin faces fresh downturn

From 🇿🇦 The Money Show, published at 2025-12-01 18:35

Stephen Grootes speaks to Busi Mavuso, CEO of Business Leadership South Africa, about why the upcoming appointment of the National Director of Public Prosecutions is pivotal for South Africa’s business climate, highlighting how rule of law failures drive up transaction costs and why structural reforms are essential to empower the new NDPP beyond just the selection process. In  other interviews, Carel de Jager, Research lead for Blockchain technology at the CSIR explains the renewed cryptocurrency sell-off, as Bitcoin slid to around $86,553 and Ethereum dropped to $2,836 amid global risk-off sentiment and regulatory pressures from China. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape.    Thank you for listening to a podcast from The Money Show    Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk   For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe   Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc   The Money Show is brought to you by Absa     Follow us on social media   702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702   CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

The Voice of the Dead (and other horror stories)

From 🇲🇽 Relatos de la Noche, published at 2025-12-01 18:00

In this episode of Relatos de la Noche, death is not an end… but a presence that insists on being heard. Join us through four testimonies that begin with a scream in a funeral home and end deep in the wilderness, where voices —and shadows— seem to have a purpose we cannot comprehend. Stories of family, of distant fields, of solitary roads, and of nights when something calls your name or watches you from the darkness. We don't know if they are warnings, farewells, or something more ancient… but tonight, we will walk together as far as those voices allow us to go. You are listening to Relatos de la Noche. — 📖 You can now get our book in physical and digital bookstores. Look for it in your favorite store or follow the link for Mexico: https://www.amazon.com.mx/Relatos-noche-Uriel-Reyes/dp/6073836201/ Spain: https://www.amazon.es/Relatos-noche-Novela-Uriel-Reyes/dp/8410442205/ Chile: https://www.buscalibre.cl/libro-relatos-de-la-noche/9789568883270/p/64600265  See omnystudio.com/listener for privacy information.

#1377: European secret services intervene

From 🇳🇱 Boekestijn en De Wijk, published at 2025-12-01 17:40

Chaotic Ukraine talks | Power grab in South America | Israel loses supportSee omnystudio.com/listener for privacy information.

The Way to Iyad with Iyad Al-Mawji

From 🇪🇬 اشتري مني, published at 2025-12-01 17:27

Contrary to expectations, we never imagined this episode could be made one day, but here we are, we really put ourselves through it, and in the end, they turned out to be friends and loved ones. A new episode with Iyad El Mougy, and we didn't mention anyone at all in this episode.

An art movement built on ancestral wisdom | Jackie Lebo

From 🇺🇸 TED Talks Daily, published at 2025-12-01 17:06

"How are the children? How are the cattle? Is it raining?" Filmmaker Jackie Lebo discovered the meaning of this traditional greeting when she and nine other artists explored Turkana, an isolated part of Kenya where the discovery of oil has disrupted pastoral life. Through film, photography and music, she and musicians Elizabeth Korikel and Eddie Grey share the deep cultural roots of art — and highlight the true connectedness of humanity. Hosted on Acast. See acast.com/privacy for more information.

Book Report – Grażyna Plebanek 'Pola'

From 🇵🇱 Raport o stanie świata Dariusza Rosiaka, published at 2025-12-01 16:00

"Polka. A word in which life resides. I clung to it like a promise" – writes Grażyna Plebanek, the only granddaughter of her grandmother, Apolonia Machczyńska-Świątek. Apolonia Machczyńska-Świątek hid Jews during World War II who managed to escape the liquidation of the Kock ghetto. In January 1943, she was shot by the Germans. Thanks to the testimony of one of the rescued Jewish women, Rywka Goldfinger, she was honored with the title of Righteous Among the Nations. Much has been written and said about Apolonia, called Pola by her loved ones. Always in the context of her death — a martyr's, monumental death. But Grażyna Plebanek wrote a book about her life. Although, as she admits, it was difficult: "Because grandmother died many times. In Annopol, at the place of her execution. In a German's testimony. In reports. On stage." The key to writing a story about her grandmother in the light of her life, not in the shadow of her death, was to free her history from the tragic myth in which she did not decide her own fate, but was sacrificed. Grażyna Plebanek followed the trail of words and sentences that contained movement and life. That is why her book "Pola. The Hidden Life of Apolonia Machczyńska-Świątek" is best discussed in motion. That's exactly what we did, arranging a walk around Brussels, the city where the author has lived for 20 years. The story of Brussels – a city in motion, constantly rebuilding, bustling, noisy, and captivating – intertwines with the story of the life of Apolonia, Pola, the Polish woman. Hosted by: Agata Kasprolewicz Guest: Grażyna Plebanek Books: "Pola. The Hidden Life of Apolonia Machczyńska-Świątek" / Agora Publishing House "Brussels. Animality in the City" / Wielka Litera Publishing House --------------------------------------------- Report on the State of the World is a program that exists thanks to our Patrons; join the fundraising ➡️ https://patronite.pl/DariuszRosiak Subscribe to the Report on the State of the World newsletter ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠➡️ https://dariuszrosiak.substack.com Report T-shirts and mugs ➡️ https://patronite-sklep.pl/kolekcja/raport-o-stanie-swiata/ [Self-promotion]

When will the Wellerman come? (Remix) [The Answer]

From 🇮🇱 התשובה עם דורון פישלר Hatshuva With Doron Fishler, published at 2025-12-01 15:02

A fresh take on the classic episode of the answer: Where did this strange song everyone is singing on TikTok come from, how did a 150-year-old inside joke make its way from New Zealand to your phone, and what on earth is a Wellerman? Including the full version of the hit "A Pharmacist Will Come Soon".

We Built Pakistan’s BIGGEST Donut Brand!! Ft. Rayyan Sohail | 480 | TBT

From 🇵🇰 Thought Behind Things, published at 2025-12-01 14:59

In this episode of Thought Behind Things, we sit down with Rayyan, the entrepreneur behind one of Pakistan’s fastest-growing food brands - OD.From a disciplined childhood in madrassah to running his father’s company at a young age, Rayyan’s journey is a mix of family pressure, resilience, and a deep desire to build something of his own. He shares how he transformed a family business, shifted from textiles to food, burned through cash in restaurants, sold his company, and then partnered with the same buyers to build OD into a national franchise.We explore:Growing up as the first-born Cash flow, failures & the reality of the restaurant businessScaling OD, acquiring it back & running a franchise-only modelLocation strategy, operations, and how to build a food business that lastsThe future of Pakistani brands and Pakistan in 2050A deep dive into business, leadership, family pressure, and the journey of building modern Pakistani brands.Socials:TBT’s Instagram: ⁠⁠⁠https://www.instagram.com/thoughtbehindthings/⁠⁠⁠TBT’s TikTok:⁠⁠⁠ https://www.tiktok.com/@tbtbymuzamil⁠⁠⁠TBT’s Facebook: ⁠⁠⁠https://www.facebook.com/thoughtbehindthings⁠⁠⁠TBT Clips: ⁠⁠⁠https://www.youtube.com/@tbtpodcastclips⁠⁠⁠Muzamil's Instagram: ⁠⁠⁠https://www.instagram.com/muzamilhasan/⁠⁠⁠Muzamil's LinkedIn: ⁠⁠⁠https://www.linkedin.com/in/muzamilhasan/⁠⁠⁠Rayyan's Instagram: https://www.instagram.com/rayyansohail/Endeavor's LinkedIn: ⁠⁠⁠https://www.linkedin.com/company/endeavor-pakistan⁠⁠⁠Special thanks to Kickstart for providing us with the studio space.You can find out more about them at: ⁠⁠⁠https://kickstart.pk/⁠⁠⁠Credits:Executive Producer: Syed Muzamil Hasan ZaidiAssociate Producer: Saad ShehryarPublisher: Talha ShaikhEditor: Jawad Sajid

Weird ways Ben Horowitz makes Founders more confident

From 🇺🇸 My First Million, published at 2025-12-01 12:39

Steal Sam's playbook to turn ChatGPT into your Executive Coach: https://clickhubspot.com/ohv Episode 770: Sam Parr ( ⁠https://x.com/theSamParr⁠ ) and Shaan Puri ( ⁠https://x.com/ShaanVP⁠ ) talk to Ben Horowitz ( https://x.com/bhorowitz ) about the Tupac murder, how to be a great leader, and the best opportunities for young people. — Show Notes: (0:00) Intro (5:36) Why most leadership books don't work (9:25) What to do when your CTO is an asshole (17:54) What makes Zuck a great CEO (27:09) #1 reason why founders fail as CEOs (33:10) Startups solving America's problems (39:19) Opportunities for young people (44:25) Culture rules with shock value (55:25) Jeff Bezos' new startup (57:00) Ben's uncommon traits (1:00:13) Wisdom accelerators (1:03:24) Paid in Full — Links: • High Output Management - https://tinyurl.com/yejpnfs8 • The Motive - https://tinyurl.com/2ba2p52m • a16z - https://a16z.com/ • KoBold Metals - https://koboldmetals.com/ • Flock Safety - https://www.flocksafety.com/ • Paid In Full - https://paidinfullfoundation.org/ — Check Out Shaan's Stuff: • Shaan's weekly email - https://www.shaanpuri.com • Visit https://www.somewhere.com/mfm to hire worldwide talent like Shaan and get $500 off for being an MFM listener. Hire developers, assistants, marketing pros, sales teams and more for 80% less than US equivalents. • Mercury - Need a bank for your company? Go check out Mercury (mercury.com). Shaan uses it for all of his companies! Mercury is a financial technology company, not an FDIC-insured bank. Banking services provided by Choice Financial Group, Column, N.A., and Evolve Bank & Trust, Members FDIC — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam’s List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by HubSpot Media // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano //

From 🇿🇦 MacG's Podcast & Chill, published at 2025-12-01 12:30

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